Systemic silencing of PHD2 causes reversible immune regulatory dysfunction.

Yamamoto, Atsushi; Hester, Joanna; Macklin, Philip S; Kawai, Kento; Uchiyama, Masateru; Biggs, Daniel; Bishop, Tammie; Bull, Katherine; Cheng, Xiaotong; Cawthorne, Eleanor; Coleman, Mathew L; Crockford, Tanya L; Davies, Ben; Dow, Lukas E; Goldin, Rob; Kranc, Kamil; Kudo, Hiromi; Lawson, Hannah; McAuliffe, James; Milward, Kate; Scudamore, Cheryl L; Soilleux, Elizabeth; Issa, Fadi; Ratcliffe, Peter J; Pugh, Chris W

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Authors

Yamamoto, Atsushi

Hester, Joanna

Macklin, Philip S

Kawai, Kento

Uchiyama, Masateru

Biggs, Daniel

Bishop, Tammie

Publication Date

2019-06-04

Journal Title

The Journal of clinical investigation

ISSN

0021-9738

Volume

129

Issue

Pages

3640-3656

Language

eng

Type

Article

This Version

VoR

Physical Medium

Electronic

Metadata

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Citation

Yamamoto, A., Hester, J., Macklin, P. S., Kawai, K., Uchiyama, M., Biggs, D., Bishop, T., et al. (2019). Systemic silencing of PHD2 causes reversible immune regulatory dysfunction.. The Journal of clinical investigation, 129 (9), 3640-3656. https://doi.org/10.1172/jci124099

Keywords

Animals, Mice, Transgenic, Mice, Signal Transduction, RNA Interference, T-Lymphocytes, Regulatory, Basic Helix-Loop-Helix Transcription Factors, Hypoxia-Inducible Factor-Proline Dioxygenases

Identifiers

External DOI: https://doi.org/10.1172/jci124099

This record's URL: https://www.repository.cam.ac.uk/handle/1810/300213

Rights

Attribution 4.0 International

Licence URL: https://creativecommons.org/licenses/by/4.0/

Except where otherwise noted, this item's licence is described as Attribution 4.0 International