Automated Insulin Delivery in Adults.
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Publication Date
2020-03Journal Title
Endocrinol Metab Clin North Am
ISSN
0889-8529
Publisher
Elsevier BV
Volume
49
Issue
1
Pages
167-178
Language
eng
Type
Article
This Version
AM
Physical Medium
Print-Electronic
Metadata
Show full item recordCitation
Boughton, C., & Hovorka, R. (2020). Automated Insulin Delivery in Adults.. Endocrinol Metab Clin North Am, 49 (1), 167-178. https://doi.org/10.1016/j.ecl.2019.10.007
Abstract
Hybrid closed-loop (artificial pancreas) systems have recently been introduced into clinical practice for adults with type 1 diabetes. This reflects successful translation from research studies in highly supervised settings to evaluation of the technology in free-living home settings. We review the different closed-loop approaches and the key clinical evidence supporting adoption of hybrid closed-loop systems for adults with type 1 diabetes. We also discuss the growing evidence for automated insulin delivery in pregnant women and in hospitalized patients with hyperglycemia. We consider the psychosocial impact of closed-loop systems and the challenges and potential future advancements for automated insulin delivery.
Keywords
Humans, Pregnancy in Diabetics, Diabetes Mellitus, Type 1, Hyperglycemia, Insulin, Blood Glucose, Blood Glucose Self-Monitoring, Insulin Infusion Systems, Hospitalization, Equipment Design, Pancreas, Artificial, Pregnancy, Automation, Adult, Female, Male
Sponsorship
National Institute of Diabetes and Digestive and Kidney Diseases (UC4DK108520)
National Institute of Diabetes and Digestive and Kidney Diseases (DP3DK112176)
Identifiers
External DOI: https://doi.org/10.1016/j.ecl.2019.10.007
This record's URL: https://www.repository.cam.ac.uk/handle/1810/300531
Rights
Attribution-NonCommercial-NoDerivatives 4.0 International
Licence URL: https://creativecommons.org/licenses/by-nc-nd/4.0/
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