Automated Insulin Delivery in Adults.
Endocrinol Metab Clin North Am
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Boughton, C., & Hovorka, R. (2020). Automated Insulin Delivery in Adults.. Endocrinol Metab Clin North Am, 49 (1), 167-178. https://doi.org/10.1016/j.ecl.2019.10.007
Hybrid closed-loop (artificial pancreas) systems have recently been introduced into clinical practice for adults with type 1 diabetes. This reflects successful translation from research studies in highly supervised settings to evaluation of the technology in free-living home settings. We review the different closed-loop approaches and the key clinical evidence supporting adoption of hybrid closed-loop systems for adults with type 1 diabetes. We also discuss the growing evidence for automated insulin delivery in pregnant women and in hospitalized patients with hyperglycemia. We consider the psychosocial impact of closed-loop systems and the challenges and potential future advancements for automated insulin delivery.
Humans, Pregnancy in Diabetics, Diabetes Mellitus, Type 1, Hyperglycemia, Insulin, Blood Glucose, Blood Glucose Self-Monitoring, Insulin Infusion Systems, Hospitalization, Equipment Design, Pancreas, Artificial, Pregnancy, Automation, Adult, Female, Male
National Institute of Diabetes and Digestive and Kidney Diseases (UC4DK108520)
National Institute of Diabetes and Digestive and Kidney Diseases (DP3DK112176)
External DOI: https://doi.org/10.1016/j.ecl.2019.10.007
This record's URL: https://www.repository.cam.ac.uk/handle/1810/300531
Attribution-NonCommercial-NoDerivatives 4.0 International
Licence URL: https://creativecommons.org/licenses/by-nc-nd/4.0/