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dc.contributor.authorTarkin, Jasonen
dc.contributor.authorGopalan, Deepaen
dc.contributor.authorMason, Justin Cen
dc.date.accessioned2020-01-09T00:31:11Z
dc.date.available2020-01-09T00:31:11Z
dc.date.issued2020-04en
dc.identifier.issn2380-6583
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/300638
dc.description.abstractA 28-year-old woman presented with atypical chest pain and long-standing upper limb claudication. She had no cardiovascular risk factors. Radial and brachial pulses were absent and blood pressure un-recordable. Investigation revealed bilateral calcified coronary aneurysms (Figure 1), with significant proximal left anterior descending and right coronary artery stenoses immediately distal to the aneurysms. Magnetic resonance imaging confirmed the underlying diagnosis of Takayasu arteritis, with multiple artery occlusions, well-developed collaterals and no evidence of active vasculitis. Stress echocardiography excluded inducible myocardial ischemia. Known as “pulse-less” disease, Takayasu arteritis typically affects young females, resulting in granulomatous large-vessel vasculitis with arterial stenoses, occlusions and aneurysms.1 Although the pattern of coronary disease in this case is highly unique, coronary involvement is not infrequent and is often overlooked.2 As there was no evidence for active vasculitis or myocardial ischemia identified, management was conservative.
dc.format.mediumPrinten
dc.languageengen
dc.publisherAmerican Medical Association
dc.rightsAll rights reserved
dc.rights.uri
dc.subjectArmen
dc.subjectHumansen
dc.subjectIntermittent Claudicationen
dc.subjectChest Painen
dc.subjectAdulten
dc.subjectFemaleen
dc.subjectTakayasu Arteritisen
dc.subjectComputed Tomography Angiographyen
dc.titleA Woman in Her 20s With Chest Pain and Arm Claudication.en
dc.typeArticle
prism.issueIdentifier4en
prism.publicationDate2020en
prism.publicationNameJAMA cardiologyen
prism.startingPage482
prism.volume5en
dc.identifier.doi10.17863/CAM.47712
dcterms.dateAccepted2019-11-04en
rioxxterms.versionofrecord10.1001/jamacardio.2019.5447en
rioxxterms.versionAM
rioxxterms.licenseref.urihttp://www.rioxx.net/licenses/all-rights-reserveden
rioxxterms.licenseref.startdate2020-04en
dc.contributor.orcidTarkin, Jason [0000-0002-9132-120X]
dc.contributor.orcidMason, Justin C [0000-0001-7783-1660]
dc.identifier.eissn2380-6591
rioxxterms.typeJournal Article/Reviewen
pubs.funder-project-idWellcome Trust (211100/Z/18/Z)
cam.orpheus.counter2*
rioxxterms.freetoread.startdate2100-01-01


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