The use of oral antibiotics and mechanical bowel preparation in elective colorectal resection for the reduction of surgical site infection.
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Duff, S., Battersby, C., Davies, R., Hancock, L., Pipe, J., Buczacki, S., Kinross, J., et al. (2020). The use of oral antibiotics and mechanical bowel preparation in elective colorectal resection for the reduction of surgical site infection.. Colorectal Dis, 22 (4), 364-372. https://doi.org/10.1111/codi.14982
Surgical site infection (SSI) is a major cause of morbidity following elective colorectal resection worldwide. Reduction in SSI rates can be achieved with the use of SSI reduction bundles. Debate about the role of mechanical bowel preparation and oral antibiotics (MOAB) in reducing SSI has persisted over decades with considerable variation in international practice. This article summarises the arguments for and against the routine use of MOAB in the elective setting, highlighting the areas of controversy and evidence gaps and provides pragmatic suggestions for colorectal practice.
Humans, Surgical Wound Infection, Colorectal Neoplasms, Cathartics, Anti-Bacterial Agents, Antibiotic Prophylaxis, Preoperative Care, Administration, Oral, Elective Surgical Procedures
This topical debate paper was commissioned by the President and Executive of the Association of Coloproctology of Great Britain and Ireland. ACPGBI also funded the open access publication fee. The authors would like to thank Ms J Pipe for her comments from the patient perspective and Miss N Fearnhead for her support in developing this debate article.
Medical Research Council (MC_PC_17230)
External DOI: https://doi.org/10.1111/codi.14982
This record's URL: https://www.repository.cam.ac.uk/handle/1810/300677
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