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Neural activity in human ventromedial prefrontal cortex reflecting the intention to save reward.

Accepted version
Peer-reviewed

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Type

Article

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Authors

Zangemeister, Leopold 
Grabenhorst, Fabian  ORCID logo  https://orcid.org/0000-0002-6455-0648

Abstract

Saving behavior usually requires individuals to perform several consecutive choices before collecting the final reward. The overt behavior is preceded by an intention to perform an appropriate choice sequence. We studied saving sequences for which each participant rated the intention numerically as willingness to save. Each sequence resulted in a specific reward amount and thus had a particular value for the participant, which we assessed with a Becker-DeGroot-Marschak auction-like mechanism. Using functional MRI, we found that blood-oxygen-level-dependent signals in human ventromedial prefrontal cortex (vmPFC) correlated with the participant's stated intention before each choice sequence. An adjacent vmPFC region showed graded activation that reflected the value of the sequence. These results demonstrate an involvement of vmPFC in intentional processes preceding sequential economic choices.

Description

Keywords

BDM, choice, functional MRI, planning, sequence, Adult, Choice Behavior, Female, Humans, Intention, Magnetic Resonance Imaging, Male, Prefrontal Cortex, Reward

Journal Title

Soc Cogn Affect Neurosci

Conference Name

Journal ISSN

1749-5016
1749-5024

Volume Title

14

Publisher

Oxford University Press (OUP)

Rights

All rights reserved
Sponsorship
Wellcome Trust (204811/Z/16/Z)
Wellcome Trust (095495/Z/11/Z)
European Research Council (293549)
Wellcome Trust (206207/Z/17/Z)