MRI of Bladder Cancer: Local and Nodal Staging.
Vargas, Hebert A
Journal of magnetic resonance imaging : JMRI
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Caglic, I., Panebianco, V., Vargas, H. A., Bura, V., Woo, S., Pecoraro, M., Cipollari, S., et al. (2020). MRI of Bladder Cancer: Local and Nodal Staging.. Journal of magnetic resonance imaging : JMRI, 52 (3), 649-667. https://doi.org/10.1002/jmri.27090
Accurate staging of bladder cancer (BC) is critical, with local tumour staging directly influencing management decisions, and affecting prognosis. However, clinical staging based on clinical examination including cystoscopy and transurethral resection of bladder tumour often under-stages patients compared to final pathology at radical cystectomy and lymph node dissection, mainly due to underestimation of the depth of local invasion and presence lymph node metastasis. MRI has now become established as the modality of choice for the local staging of BC and can be additionally utilized for the assessment of regional lymph node involvement and tumour spread to the pelvic bones and upper urinary tract. The recent development of the Vesical Imaging-Reporting And Data System (VI-RADS) recommendations has led to further improvements in bladder MRI, enabling standardization of image acquisition and reporting. Multiparametric MRI (mpMRI) incorporating morphological and functional imaging has been proven to further improve the accuracy of primary and recurrent tumour detection and local staging, and has shown promise in predicting tumour aggressiveness and monitoring response to therapy. These sequences can also be utilised to perform radiomics which has shown encouraging initial results in predicting BC grade and local stage. In this article, the current state of evidence supporting MRI in local, regional and distant staging in patients with bladder cancer is reviewed.
Humans, Neoplasm Recurrence, Local, Magnetic Resonance Imaging, Neoplasm Staging, Urinary Bladder Neoplasms, Multiparametric Magnetic Resonance Imaging
External DOI: https://doi.org/10.1002/jmri.27090
This record's URL: https://www.repository.cam.ac.uk/handle/1810/301279
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