Therapy-induced tumour secretomes promote resistance and tumour progression.

Obenauf, Anna C; Zou, Yilong; Ji, Andrew L; Vanharanta, Sakari; Shu, Weiping; Shi, Hubing; Kong, Xiangju; Bosenberg, Marcus C; Wiesner, Thomas; Rosen, Neal; Lo, Roger S; Massagué, Joan

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Authors

Obenauf, Anna C

Zou, Yilong

Ji, Andrew L

Vanharanta, Sakari

Shu, Weiping

Shi, Hubing

Kong, Xiangju

Publication Date

2015-04

Journal Title

Nature

ISSN

0028-0836

Volume

520

Issue

7547

Pages

368-372

Language

eng

Type

Article

This Version

Physical Medium

Print-Electronic

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Citation

Obenauf, A. C., Zou, Y., Ji, A. L., Vanharanta, S., Shu, W., Shi, H., Kong, X., et al. (2015). Therapy-induced tumour secretomes promote resistance and tumour progression.. Nature, 520 (7547), 368-372. https://doi.org/10.1038/nature14336

Keywords

Cell Line, Tumor, Clone Cells, Animals, Humans, Mice, Melanoma, Adenocarcinoma, Lung Neoplasms, Neoplasm Metastasis, Disease Progression, Proto-Oncogene Proteins B-raf, Receptor Protein-Tyrosine Kinases, Proto-Oncogene Proteins c-fos, Protein Kinase Inhibitors, Signal Transduction, Cell Proliferation, Cell Movement, Cell Survival, Down-Regulation, Enzyme Activation, Drug Resistance, Neoplasm, Female, Proto-Oncogene Proteins c-akt, Metabolome, Tumor Microenvironment, ErbB Receptors, Anaplastic Lymphoma Kinase

Sponsorship

Medical Research Council (MC_UU_12022/7)

Identifiers

External DOI: https://doi.org/10.1038/nature14336

This record's URL: https://www.repository.cam.ac.uk/handle/1810/302059