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ANOS1: a unified nomenclature for Kallmann syndrome 1 gene (KAL1) and anosmin-1.

Published version
Peer-reviewed

Type

Article

Change log

Authors

de Castro, Fernando 
Maggi, Roberto 
Group of HGNC consultants for KAL1 nomenclature 

Abstract

It is accepted that confusion regarding the description of genetic variants occurs when researchers do not use standard nomenclature. The Human Genome Organization Gene Nomenclature Committee contacted a panel of consultants, all working on the KAL1 gene, to propose an update of the nomenclature of the gene, as there was a convention in the literature of using the 'KAL1' symbol, when referring to the gene, but using the name 'anosmin-1' when referring to the protein. The new name, ANOS1, reflects protein name and is more transferrable across species.

Description

Keywords

: Kallmann, ANOS1, KAL1, anosmin-1, gene, nomenclature, Animals, Extracellular Matrix Proteins, Humans, Kallmann Syndrome, Nerve Tissue Proteins, Terminology as Topic

Journal Title

Briefings in Functional Genomics

Conference Name

Journal ISSN

1473-9550
2041-2657

Volume Title

16

Publisher

Oxford University Press
Sponsorship
This work was supported by grants from the Spanish Ministerio de Economia y Competitividad-MINECO (SAF2012-40023 and RD12-0032-12) and Consejo Superior de Investigaciones Científicas-CSIC (CSIC-2015201023) to F.dC., from National Human Genome Research Institute (U41HG003345) and Wellcome Trust (099129/Z/12/Z) to R.S. and from Fondazione Telethon (E.523) and Ministero dell’Istruzione Universitá e Ricerca (MIUR) to R.M