ANOS1: a unified nomenclature for Kallmann syndrome 1 gene (KAL1) and anosmin-1.
Published version
Peer-reviewed
Repository URI
Repository DOI
Change log
Authors
de Castro, Fernando
Seal, Ruth https://orcid.org/0000-0002-7545-6817
Maggi, Roberto
Group of HGNC consultants for KAL1
nomenclature
Abstract
It is accepted that confusion regarding the description of genetic variants occurs when researchers do not use standard nomenclature. The Human Genome Organization Gene Nomenclature Committee contacted a panel of consultants, all working on the KAL1 gene, to propose an update of the nomenclature of the gene, as there was a convention in the literature of using the 'KAL1' symbol, when referring to the gene, but using the name 'anosmin-1' when referring to the protein. The new name, ANOS1, reflects protein name and is more transferrable across species.
Description
Keywords
: Kallmann, ANOS1, KAL1, anosmin-1, gene, nomenclature, Animals, Extracellular Matrix Proteins, Humans, Kallmann Syndrome, Nerve Tissue Proteins, Terminology as Topic
Journal Title
Briefings in Functional Genomics
Conference Name
Journal ISSN
1473-9550
2041-2657
2041-2657
Volume Title
16
Publisher
Oxford University Press
Publisher DOI
Sponsorship
This work was supported by grants from the Spanish Ministerio de Economia y Competitividad-MINECO (SAF2012-40023 and RD12-0032-12) and Consejo Superior de Investigaciones Científicas-CSIC (CSIC-2015201023) to F.dC., from National Human Genome Research Institute (U41HG003345) and Wellcome Trust (099129/Z/12/Z) to R.S. and from Fondazione Telethon (E.523) and Ministero dell’Istruzione Universitá e Ricerca (MIUR) to R.M