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Closed-loop insulin delivery system enhances type 1 diabetes glycemic control.

Accepted version
Peer-reviewed

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Type

Article

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Authors

Fuchs, Julia 

Abstract

Brown SA, Kovatchev BP, Raghinaru D, Lum JW, Buckingham BA, Kudva YC, et al. Six-Month Randomized, Multicenter Trial of Closed-Loop Control in Type 1 Diabetes. N Engl J Med 2019;381:1707-17.

Question Among patients with type 1 diabetes, what is the therapeutic efficacy of a closed-loop system (that detects glucose and administers insulin), compared with a sensor-augmented system (that requires user input), in keeping glucose levels within 70 to 180 mg per deciliter?

Description

Keywords

Blood Glucose, Diabetes Mellitus, Type 1, Humans, Hypoglycemic Agents, Insulin, Insulin Infusion Systems, Pancreas, Artificial

Journal Title

J Pediatr

Conference Name

Journal ISSN

0022-3476
1097-6833

Volume Title

218

Publisher

Elsevier BV
Sponsorship
Cambridge University Hospitals NHS Foundation Trust (CUH) (146281)
National Institute of Diabetes and Digestive and Kidney Diseases (R01DK085621)
National Institute of Diabetes and Digestive and Kidney Diseases (DP3DK112176)