Cardiometabolic Risk Factors in Pregnancy and Implications for Long-Term Health: Identifying the Research Priorities for Low-Resource Settings
Kennedy, Stephen H.
Hirst, Jane E.
Frontiers in Cardiovascular Medicine
Frontiers Media S.A.
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Nagraj, S., Kennedy, S. H., Norton, R., Jha, V., Praveen, D., Hinton, L., & Hirst, J. E. (2020). Cardiometabolic Risk Factors in Pregnancy and Implications for Long-Term Health: Identifying the Research Priorities for Low-Resource Settings. Frontiers in Cardiovascular Medicine, 7 https://doi.org/10.3389/fcvm.2020.00040
Cardiometabolic disorders (CMDs), including ischemic heart disease, stroke and type 2 diabetes are the leading causes of mortality and morbidity in women worldwide. The burden of CMDs falls disproportionately on low and middle-income countries (LMICs), placing substantial demands on already pressured health systems. Cardiometabolic disorders may present up to a decade earlier in some LMIC settings, and are associated with high-case fatality rates. Early identification and ongoing postpartum follow-up of women with pregnancy complications such as hypertensive disorders of pregnancy (HDPs), and gestational diabetes mellitus (GDM) may offer opportunities for prevention, or help delay onset of CMDs. This mini-review paper presents an overview of the key challenges faced in the early identification, referral and management of pregnant women at increased risk of CMDs, in low-resource settings worldwide. Evidence-based strategies, including novel diagnostics, technology and innovations for early detection, screening and management for pregnant women at high-risk of CMDs are presented. The review highlights the key research priorities for addressing cardiometabolic risk in pregnancy in low-resource settings.
Cardiovascular Medicine, high-risk pregnancy, preeclampsia, gestational diabetes, cardiometabolic disorders, cardiovascular disease
External DOI: https://doi.org/10.3389/fcvm.2020.00040
This record's URL: https://www.repository.cam.ac.uk/handle/1810/304056
Attribution 4.0 International (CC BY 4.0)
Licence URL: https://creativecommons.org/licenses/by/4.0/