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A guide to naming human non-coding RNA genes.

Published version
Peer-reviewed

Type

Article

Change log

Authors

Chen, Ling-Ling 
Griffiths-Jones, Sam 
Lowe, Todd M 
Mathews, Michael B 

Abstract

Research on non-coding RNA (ncRNA) is a rapidly expanding field. Providing an official gene symbol and name to ncRNA genes brings order to otherwise potential chaos as it allows unambiguous communication about each gene. The HUGO Gene Nomenclature Committee (HGNC, www.genenames.org) is the only group with the authority to approve symbols for human genes. The HGNC works with specialist advisors for different classes of ncRNA to ensure that ncRNA nomenclature is accurate and informative, where possible. Here, we review each major class of ncRNA that is currently annotated in the human genome and describe how each class is assigned a standardised nomenclature.

Description

Keywords

gene nomenclature, gene symbols, non-coding RNA, Genome, Human, Humans, RNA, Untranslated, Terminology as Topic

Journal Title

EMBO J

Conference Name

Journal ISSN

0261-4189
1460-2075

Volume Title

39

Publisher

Springer Science and Business Media LLC