Severe Paradoxical Disease Activation Following Alemtuzumab Treatment for Multiple Sclerosis.
Published version
Peer-reviewed
Repository URI
Repository DOI
Type
Article
Change log
Authors
Jones, Joanne
Stacpoole, Sybil
Brannigan, James
Abstract
A 39-year old right-handed agricultural service engineer developed rapidly evolving severe relapsing-remitting Multiple Sclerosis (MS). MR imaging showed multiple T2 hyperintensities throughout his neuro-axis (Figure 1A). Several lesions showed restricted diffusion, and two enhanced. He received steroids for each relapse, making a full recovery (EDSS 0).
Description
Keywords
Adult, Alemtuzumab, Electroencephalography, Humans, Immunologic Factors, Magnetic Resonance Imaging, Multiple Sclerosis, Relapsing-Remitting
Journal Title
Neurology: Neuroimmunology and NeuroInflammation
Conference Name
Journal ISSN
2332-7812
2332-7812
2332-7812
Volume Title
7
Publisher
Lippincott Williams and Wilkins
Publisher DOI
Sponsorship
Wellcome Trust (105924/Z/14/Z)
Wellcome Trust (105924/Z/14/A)
Wellcome Trust (105924/Z/14/Z)
Wellcome Trust (105924/Z/14/A)
Wellcome Trust (105924/Z/14/A)
Wellcome Trust (105924/Z/14/Z)
Wellcome Trust (105924/Z/14/A)
Wellcome Trust