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Rare non-Hodgkin lymphoma of childhood and adolescence: A consensus diagnostic and therapeutic approach to pediatric-type follicular lymphoma, marginal zone lymphoma, and nonanaplastic peripheral T-cell lymphoma.

Accepted version
Peer-reviewed

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Type

Article

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Authors

Attarbaschi, Andishe  ORCID logo  https://orcid.org/0000-0002-9285-6898
Abla, Oussama 
Arias Padilla, Laura 
Beishuizen, Auke 
Burke, GA Amos 

Abstract

Pediatric-type follicular (PTFL), marginal zone (MZL), and peripheral T-cell lymphoma (PTCL) account each for <2% of childhood non-Hodgkin lymphoma. We present clinical and histopathological features of PTFL, MZL, and few subtypes of PTCL and provide treatment recommendations. For localized PTFL and MZL, watchful waiting after complete resection is the therapy of choice. For PTCL, therapy is subtype-dependent and ranges from a block-like anaplastic large cell lymphoma (ALCL)-derived and, alternatively, leukemia-derived therapy in PTCL not otherwise specified and subcutaneous panniculitis-like T-cell lymphoma to a block-like mature B-NHL-derived or, preferentially, ALCL-derived treatment followed by hematopoietic stem cell transplantation in first remission in hepatosplenic and angioimmunoblastic T-cell lymphoma.

Description

Keywords

follicular lymphoma, marginal zone lymphoma, non-Hodgkin lymphoma, peripheral T-cell lymphoma, rare, Adolescent, Allografts, Child, Child, Preschool, Female, Hematopoietic Stem Cell Transplantation, Humans, Infant, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Follicular, Lymphoma, T-Cell, Peripheral, Male

Journal Title

Pediatr Blood Cancer

Conference Name

Journal ISSN

1545-5009
1545-5017

Volume Title

67

Publisher

Wiley

Rights

All rights reserved