Guest Binding Drives Host Redistribution in Libraries of CoII 4 L4 Cages.
Accepted version
Peer-reviewed
Repository URI
Repository DOI
Change log
Authors
Kieffer, Marion https://orcid.org/0000-0003-0202-7445
Bilbeisi, Rana A
Thoburn, John D
Clegg, Jack K https://orcid.org/0000-0002-7140-5596
Nitschke, Jonathan R https://orcid.org/0000-0002-4060-5122
Abstract
Two CoII 4 L4 tetrahedral cages prepared from similar building blocks showed contrasting host-guest properties. One cage did not bind guests, whereas the second encapsulated a series of anions, due to electronic and geometric effects. When the building blocks of both cages were present during self-assembly, a library of five CoII LA x LB 4-x cages was formed in a statistical ratio in the absence of guests. Upon incorporation of anions able to interact preferentially with some library members, the products obtained were redistributed in favor of the best anion binders. To quantify the magnitudes of these templation effects, ESI-MS was used to gauge the effect of each template upon library redistribution.
Description
Keywords
host-guest systems, mass spectrometry, metal-organic Cages, self-assembly, supramolecular library
Journal Title
Angew Chem Int Ed Engl
Conference Name
Journal ISSN
1433-7851
1521-3773
1521-3773
Volume Title
59
Publisher
Wiley
Publisher DOI
Rights
All rights reserved
Sponsorship
Engineering and Physical Sciences Research Council (EP/P027067/1)
European Commission (642192)
European Commission (642192)