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dc.contributor.authorMookerjee, Souradipen
dc.contributor.authorFoster, HRen
dc.contributor.authorWaller, Amieen
dc.contributor.authorGhevaert, Cedricen
dc.date.accessioned2020-05-13T23:30:52Z
dc.date.available2020-05-13T23:30:52Z
dc.date.issued2020-08en
dc.identifier.issn0953-7104
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/305377
dc.description.abstractPlatelet transfusions are given to patients in hospital who have a low blood platelet count (thrombocytopenia) either because of major bleeding (following trauma or surgery) or because the bone marrow production of platelets is impaired often due to chemotherapy, infiltration with malignant cells, fibrosis or genetic disorders. We are currently entirely reliant on blood donors as a source of platelets in transfusion medicine. However, the demand for platelets continues to rise, driven by an ageing population, advances in medical procedures and ever more aggressive cancer therapies, while the supply of blood donors continues to remain static.
dc.description.sponsorshipThis work was supported by grants from the Rosetrees Trust (A1691), NHS Blood and Transplant and the European Union (SilkFusion: AMD-767309-3).
dc.format.mediumPrint-Electronicen
dc.languageengen
dc.publisherTaylor & Francis
dc.rightsAll rights reserved
dc.rights.uri
dc.subjectBlood Plateletsen
dc.subjectHumansen
dc.subjectCell Culture Techniquesen
dc.titleIn vitro-derived platelets: the challenges we will have to face to assess quality and safety.en
dc.typeArticle
prism.endingPage730
prism.issueIdentifier6en
prism.publicationDate2020en
prism.publicationNamePlateletsen
prism.startingPage724
prism.volume31en
dc.identifier.doi10.17863/CAM.52460
dcterms.dateAccepted2020-05-09en
rioxxterms.versionofrecord10.1080/09537104.2020.1769051en
rioxxterms.versionAM
rioxxterms.licenseref.urihttp://www.rioxx.net/licenses/all-rights-reserveden
rioxxterms.licenseref.startdate2020-08en
dc.contributor.orcidMookerjee, Souradip [0000-0003-4904-1324]
dc.contributor.orcidFoster, HR [0000-0001-8118-9842]
dc.contributor.orcidWaller, Amie [0000-0002-9726-5560]
dc.contributor.orcidGhevaert, Cedric [0000-0002-9251-0934]
dc.identifier.eissn1369-1635
rioxxterms.typeJournal Article/Reviewen
pubs.funder-project-idRosetrees Trust (A1691)
pubs.funder-project-idEuropean Commission Horizon 2020 (H2020) Future and Emerging Technologies (FET) (767309)
pubs.funder-project-idMRC (MC_PC_12009)
pubs.funder-project-idMedical Research Council (MC_PC_17230)
cam.orpheus.successMon Jun 08 08:21:36 BST 2020 - Embargo updated*
cam.orpheus.counter3*
rioxxterms.freetoread.startdate2021-06-02


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