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Data to support: Intra-articular AAV-PHP.S mediated chemogenetic targeting of knee-innervating dorsal root ganglion neurons alleviates inflammatory pain in mice


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Authors

Chakrabarti, Sampurna 
Pattison, Luke 
Doleschall, Balint 
Rickman, Rebecca 
Blake, Helen 

Description

The files contain the raw data to support the publication and are organised into separate files, each one corresponding to a different figure in the paper.

Alongside the raw data, the statistical analyses used in the published paper are presented.

File Fig1_S1_virus contains all the raw data relating to Figure 1 and Figure S1 in terms of the number of positive cells for the different markers described.

File Fig 2_S3_virus contains all the raw data and analysis for electrophysiology and behavioural experiments with the GqDREADD construct, relating to Figure 2 and Figure S3

File Fig3_S4_virus contains all the raw data and analysis for electrophysiology and behavioural experiments with the GiDREADD construct, relating to Figure 3 and Figure S4

File FigS2_virus contains all the raw data and analysis for electrophysiology and behavioural experiments with compound 21 in animals without DREADD expression.

Version

Software / Usage instructions

All files open with Graphpad Prism

Keywords

Behaviour, Electrophysiology, Immunohistochemistry

Publisher

Sponsorship
ARTHRITIS RESEARCH UK (20930)
Arthritis Research UK (11600/21973)
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