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dc.contributor.authorHayes, Louiseen
dc.contributor.authorForrest, Lynneen
dc.contributor.authorAdams, Jeanen
dc.contributor.authorHidajat, Miraen
dc.contributor.authorBen-Shlomo, Yoaven
dc.contributor.authorWhite, Martinen
dc.contributor.authorSharp, Lindaen
dc.date.accessioned2020-06-12T23:30:21Z
dc.date.available2020-06-12T23:30:21Z
dc.date.issued2019-01en
dc.identifier.issn0143-005X
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/306745
dc.description.abstractBACKGROUND: Older people experience poorer outcomes from colon cancer. We examined if treatment for colon cancer was related to age and if inequalities changed over time. METHODS: Data from the UK population-based Northern and Yorkshire Cancer Registry on 31 910 incident colon cancers (ICD10 C18) diagnosed between 1999-2010 were obtained. Likelihood of receipt of: (1) cancer-directed surgery, (2) chemotherapy in surgical patients, (3) chemotherapy in non-surgical patients by age, adjusting for sex, area deprivation, cancer stage, comorbidity and period of diagnosis, was examined. RESULTS: Age-related inequalities in treatment exist after adjustment for confounding factors. Patients aged 60- 69, 70-79 and 80+ years were significantly less likely to receive surgery than those aged <60 years (multivariable ORs (95% CI) 0.84(0.74 to 0.95), 0.54(0.48 to 0.61) and 0.19(0.17 to 0.21), respectively). Age-related differences in receipt of surgery and adjuvant chemotherapy (but not chemotherapy in non-surgical patients) narrowed over time for the 'younger old' (aged <80 years) but did not diminish for the oldest patients. CONCLUSIONS: Age inequality in treatment of colon cancer remains after adjustment for confounders, suggesting age remains a major factor in treatment decisions. Research is needed to better understand the cancer treatment decision-making process, and how to influence this, for older patients.
dc.format.mediumPrint-Electronicen
dc.languageengen
dc.rightsAll rights reserved
dc.rights.uri
dc.subjectHumansen
dc.subjectColonic Neoplasmsen
dc.subjectNeoplasm Stagingen
dc.subjectRegistriesen
dc.subjectIncidenceen
dc.subjectAge Factorsen
dc.subjectComorbidityen
dc.subjectPatient Selectionen
dc.subjectAgeden
dc.subjectAged, 80 and overen
dc.subjectMiddle Ageden
dc.subjectEnglanden
dc.subjectFemaleen
dc.subjectMaleen
dc.subjectHealthcare Disparitiesen
dc.titleAge-related inequalities in colon cancer treatment persist over time: a population-based analysis.en
dc.typeArticle
prism.endingPage41
prism.issueIdentifier1en
prism.publicationDate2019en
prism.publicationNameJournal of epidemiology and community healthen
prism.startingPage34
prism.volume73en
dc.identifier.doi10.17863/CAM.53833
dcterms.dateAccepted2018-07-31en
rioxxterms.versionofrecord10.1136/jech-2018-210842en
rioxxterms.versionAM
rioxxterms.licenseref.urihttp://www.rioxx.net/licenses/all-rights-reserveden
rioxxterms.licenseref.startdate2019-01en
dc.contributor.orcidHayes, Louise [0000-0001-6442-4150]
dc.contributor.orcidAdams, Jean [0000-0002-5733-7830]
dc.contributor.orcidHidajat, Mira [0000-0002-7252-9574]
dc.contributor.orcidBen-Shlomo, Yoav [0000-0001-6648-3007]
dc.contributor.orcidWhite, Martin [0000-0002-1861-6757]
dc.identifier.eissn1470-2738
rioxxterms.typeJournal Article/Reviewen


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