Single-bite versus double-bite technique for mapping biopsies during endoscopic surveillance for hereditary diffuse gastric cancer: a single-centre, randomized trial
Accepted version
Peer-reviewed
Repository URI
Repository DOI
Change log
Authors
Pappas, A
Tan, Wei Keith
Waldock, William
Richardson, Susan
Abstract
Abstract Background and Aims Endoscopic surveillance is recommended in patients with Hereditary Diffuse Gastric Cancer (HDGC) that want to delay or refuse surgery. Since early signet ring cell carcinoma (SRCC) can be inconspicuous, current surveillance endoscopy protocol entails 30 random biopsies which are time-consuming. This study aimed to compare single and double-bite techniques in HDGC surveillance.
Description
Keywords
Biopsy, Cadherins, Carcinoma, Signet Ring Cell, Gastrectomy, Gastroscopy, Humans, Stomach Neoplasms
Journal Title
Endoscopy
Conference Name
Journal ISSN
0013-726X
1438-8812
1438-8812
Volume Title
53
Publisher
Thieme
Publisher DOI
Rights
All rights reserved
Sponsorship
Cancer Research UK (21102)
The study has received infrastructure support from the Experimental Cancer Medicine Center and Cambridge Biomedical Research Center. AP was funded by a CRUK Multidisciplinary Project Award (C47594/A21202).