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dc.contributor.authorDi Jiang, Caroline
dc.contributor.authorRaine, Tim
dc.date.accessioned2020-07-10T14:05:40Z
dc.date.available2020-07-10T14:05:40Z
dc.date.issued2020-07-09
dc.date.submitted2020-05-06
dc.identifier.other10.1177_1759720x20939410
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/307834
dc.description.abstractSpondyloarthritis (SpA) may be regarded a family of auto-inflammatory conditions with inflammation focused on the joints. These form part of a wider family of immune-mediated inflammatory diseases, which include inflammatory bowel diseases (IBD). These conditions share common elements of pathophysiology and it is perhaps unsurprising, therefore, that individuals with SpA frequently manifest gastrointestinal inflammation, to which the physician managing the patient with SpA must be alert. In this article, we review the shared epidemiology and pathophysiology of these conditions, before discussing approaches to diagnosis and management of inflammatory gastrointestinal pathology in patients seen in rheumatology clinics. In particular, we discuss the difference between non-specific gastrointestinal inflammation commonly described in this patient group and the more specific diagnosis of Crohn’s disease or ulcerative colitis. We describe the appropriate diagnostic workup for patients suspected of having IBD. In addition, we discuss how a diagnosis of IBD can inform treatment selection, highlighting important differences in treatment choice, drug dosing, monitoring and drug safety for this particular comorbid patient population.
dc.languageen
dc.publisherSAGE Publications
dc.rightsEmbargo: ends 2020-07-09
dc.subjectExtra-articular manifestations and comorbidities in spondyloarthritis
dc.subjectcrohn’s disease
dc.subjectinflammatory bowel disease
dc.subjectspondyloarthritis
dc.subjectulcerative colitis
dc.titleIBD considerations in spondyloarthritis
dc.typeArticle
dc.date.updated2020-07-10T14:05:39Z
prism.publicationNameTherapeutic Advances in Musculoskeletal Disease
prism.volume12
dc.identifier.doi10.17863/CAM.54929
dcterms.dateAccepted2020-06-12
rioxxterms.versionofrecord10.1177/1759720x20939410
rioxxterms.versionVoR
rioxxterms.licenseref.urihttps://creativecommons.org/licenses/by/4.0/
rioxxterms.licenseref.startdate2020-07-09
dc.contributor.orcidRaine, Tim [0000-0002-5855-9873]
dc.identifier.eissn1759-7218
rioxxterms.freetoread.startdate2020-07-09


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