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dc.contributor.authorWarrier, Varun
dc.contributor.authorGreenberg, David M
dc.contributor.authorWeir, Elizabeth
dc.contributor.authorBuckingham, Clara
dc.contributor.authorSmith, Paula
dc.contributor.authorLai, Meng-Chuan
dc.contributor.authorAllison, Carrie
dc.contributor.authorBaron-Cohen, Simon
dc.date.accessioned2020-07-16T23:31:03Z
dc.date.available2020-07-16T23:31:03Z
dc.date.issued2020-08-07
dc.identifier.issn2041-1723
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/308050
dc.description.abstractIt is unclear whether transgender and gender-diverse individuals have elevated rates of autism diagnosis or traits related to autism compared to cisgender individuals in large non-clinic-based cohorts. To investigate this, we use five independently recruited cross-sectional datasets consisting of 641,860 individuals who completed information on gender, neurodevelopmental and psychiatric diagnoses including autism, and measures of traits related to autism (self-report measures of autistic traits, empathy, systemizing, and sensory sensitivity). Compared to cisgender individuals, transgender and gender-diverse individuals have, on average, higher rates of autism, other neurodevelopmental and psychiatric diagnoses. For both autistic and non-autistic individuals, transgender and gender-diverse individuals score, on average, higher on self-report measures of autistic traits, systemizing, and sensory sensitivity, and, on average, lower on self-report measures of empathy. The results may have clinical implications for improving access to mental health care and tailoring adequate support for transgender and gender-diverse individuals.
dc.description.sponsorshipWellcome Trust Templeton World Charity Foundation Autism Research Trust
dc.format.mediumElectronic
dc.languageeng
dc.publisherSpringer Science and Business Media LLC
dc.rightsAll rights reserved
dc.subjectHumans
dc.subjectConfidence Intervals
dc.subjectOdds Ratio
dc.subjectAutistic Disorder
dc.subjectAdolescent
dc.subjectAdult
dc.subjectAged
dc.subjectAged, 80 and over
dc.subjectMiddle Aged
dc.subjectFemale
dc.subjectMale
dc.subjectYoung Adult
dc.subjectSelf Report
dc.subjectTransgender Persons
dc.titleElevated rates of autism, other neurodevelopmental and psychiatric diagnoses, and autistic traits in transgender and gender-diverse individuals.
dc.typeArticle
prism.issueIdentifier1
prism.publicationDate2020
prism.publicationNameNat Commun
prism.startingPage3959
prism.volume11
dc.identifier.doi10.17863/CAM.55145
dcterms.dateAccepted2020-07-15
rioxxterms.versionofrecord10.1038/s41467-020-17794-1
rioxxterms.versionAM
rioxxterms.licenseref.urihttp://www.rioxx.net/licenses/all-rights-reserved
rioxxterms.licenseref.startdate2020-08-07
dc.contributor.orcidWarrier, Varun [0000-0003-4532-8571]
dc.contributor.orcidWeir, Elizabeth [0000-0001-5434-9193]
dc.contributor.orcidLai, Meng-Chuan [0000-0002-9593-5508]
dc.contributor.orcidAllison, Carrie [0000-0003-2272-2090]
dc.contributor.orcidBaron-Cohen, Simon [0000-0001-9217-2544]
dc.identifier.eissn2041-1723
rioxxterms.typeJournal Article/Review
pubs.funder-project-idWellcome Trust (214322/Z/18/Z)
pubs.funder-project-idAutism Research Trust (unknown)
cam.issuedOnline2020-08-07
cam.orpheus.counter4
rioxxterms.freetoread.startdate2023-07-16


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