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Amplification of actin polymerization forces.

Published version
Peer-reviewed

Type

Article

Change log

Authors

Nédélec, François 

Abstract

The actin cytoskeleton drives many essential processes in vivo, using molecular motors and actin assembly as force generators. We discuss here the propagation of forces caused by actin polymerization, highlighting simple configurations where the force developed by the network can exceed the sum of the polymerization forces from all filaments.

Description

Keywords

Actin Cytoskeleton, Actins, Animals, Cell Movement, Humans, Mechanotransduction, Cellular, Models, Biological, Molecular Motor Proteins, Polymerization, Pseudopodia, Stress, Mechanical

Journal Title

J Cell Biol

Conference Name

Journal ISSN

0021-9525
1540-8140

Volume Title

212

Publisher

Rockefeller University Press