Practicable assessment of cochlear size and shape from clinical CT images.
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Gee, A., Zhao, Y., Treece, G., & Bance, M. (2021). Practicable assessment of cochlear size and shape from clinical CT images.. 3448. https://doi.org/10.1038/s41598-021-83059-6
There is considerable interpersonal variation in the size and shape of the human cochlea, with evident consequences for cochlear implantation. The ability to characterize a specific cochlea, from preoperative computed tomography (CT) images, would allow the clinician to personalize the choice of electrode, surgical approach and postoperative programming. In this study, we present a fast, practicable and freely available method for estimating cochlear size and shape from clinical CT. The approach taken is to fit a template surface to the CT data, using either a statistical shape model or a locally affine deformation (LAD). After fitting, we measure cochlear size, duct length and a novel measure of basal turn non-planarity, which we suggest might correlate with the risk of insertion trauma. Gold-standard measurements from a convenience sample of 18 micro-CT scans are compared with the same quantities estimated from low-resolution, noisy, pseudo-clinical data synthesized from the same micro-CT scans. The best results were obtained using the LAD method, with an expected error of 8-17% of the gold-standard sample range for non-planarity, cochlear size and duct length.
External DOI: https://doi.org/10.1038/s41598-021-83059-6
This record's URL: https://www.repository.cam.ac.uk/handle/1810/308590
Attribution 4.0 International
Licence URL: http://creativecommons.org/licenses/by/4.0/