Show simple item record

dc.contributor.authorGee, Andrewen
dc.contributor.authorZhao, Yufengen
dc.contributor.authorTreece, Grahamen
dc.contributor.authorBance, Manoharen
dc.date.accessioned2020-07-30T08:54:46Z
dc.date.available2020-07-30T08:54:46Z
dc.date.issued2021-02-10en
dc.identifier.issn2045-2322en
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/308590
dc.description.abstractThere is considerable interpersonal variation in the size and shape of the human cochlea, with evident consequences for cochlear implantation. The ability to characterize a specific cochlea, from preoperative computed tomography (CT) images, would allow the clinician to personalize the choice of electrode, surgical approach and postoperative programming. In this study, we present a fast, practicable and freely available method for estimating cochlear size and shape from clinical CT. The approach taken is to fit a template surface to the CT data, using either a statistical shape model or a locally affine deformation (LAD). After fitting, we measure cochlear size, duct length and a novel measure of basal turn non-planarity, which we suggest might correlate with the risk of insertion trauma. Gold-standard measurements from a convenience sample of 18 micro-CT scans are compared with the same quantities estimated from low-resolution, noisy, pseudo-clinical data synthesized from the same micro-CT scans. The best results were obtained using the LAD method, with an expected error of 8-17% of the gold-standard sample range for non-planarity, cochlear size and duct length.en
dc.format.mediumElectronicen
dc.rightsAttribution 4.0 Internationalen
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en
dc.titlePracticable assessment of cochlear size and shape from clinical CT images.en
dc.typeReport
prism.publicationDate2021en
prism.startingPage3448
dc.identifier.doi10.17863/CAM.55677
rioxxterms.versionofrecord10.1038/s41598-021-83059-6en
rioxxterms.licenseref.urihttp://www.rioxx.net/licenses/all-rights-reserveden
rioxxterms.licenseref.startdate2021-02-10en
dcterms.formatElectronicen
dc.contributor.orcidTreece, Graham [0000-0003-0047-6845]
dc.identifier.eissn2045-2322en
rioxxterms.typeTechnical Reporten


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record

Attribution 4.0 International
Except where otherwise noted, this item's licence is described as Attribution 4.0 International