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dc.contributor.authorIkenoue, Tatsuyaen
dc.contributor.authorAprile, Francesco Aen
dc.contributor.authorSormanni, Pietroen
dc.contributor.authorRuggeri, Francescoen
dc.contributor.authorPerni, Micheleen
dc.contributor.authorHeller, Gabriella Ten
dc.contributor.authorHaas, Christian Pen
dc.contributor.authorMiddel, Christophen
dc.contributor.authorLimbocker, Ryanen
dc.contributor.authorMannini, Benedettaen
dc.contributor.authorMichaels, Thomas CTen
dc.contributor.authorKnowles, Tuomasen
dc.contributor.authorDobson, Christopher Men
dc.contributor.authorVendruscolo, Micheleen
dc.date.accessioned2020-09-25T23:30:35Z
dc.date.available2020-09-25T23:30:35Z
dc.date.issued2020-09-17en
dc.identifier.issn2045-2322
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/310747
dc.format.mediumElectronicen
dc.languageengen
dc.rightsAttribution 4.0 International
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectAnimalsen
dc.subjectCaenorhabditis elegansen
dc.subjectAlzheimer Diseaseen
dc.subjectDisease Models, Animalen
dc.subjectAmyloiden
dc.subjectPeptide Fragmentsen
dc.subjectAmyloid beta-Peptidesen
dc.subjectPlaque, Amyloiden
dc.subjectProtein Aggregation, Pathologicalen
dc.titleA rationally designed bicyclic peptide remodels Aβ42 aggregation in vitro and reduces its toxicity in a worm model of Alzheimer's disease.en
dc.typeArticle
prism.issueIdentifier1en
prism.publicationDate2020en
prism.publicationNameScientific reportsen
prism.startingPage15280
prism.volume10en
dc.identifier.doi10.17863/CAM.57836
dcterms.dateAccepted2020-06-26en
rioxxterms.versionofrecord10.1038/s41598-020-69626-3en
rioxxterms.versionVoR
rioxxterms.licenseref.urihttp://www.rioxx.net/licenses/all-rights-reserveden
rioxxterms.licenseref.startdate2020-09-17en
dc.contributor.orcidSormanni, Pietro [0000-0002-6228-2221]
dc.contributor.orcidRuggeri, Francesco [0000-0002-1232-1907]
dc.contributor.orcidHaas, Christian P [0000-0002-9457-8019]
dc.contributor.orcidLimbocker, Ryan [0000-0002-6030-6656]
dc.contributor.orcidKnowles, Tuomas [0000-0002-7879-0140]
dc.contributor.orcidVendruscolo, Michele [0000-0002-3616-1610]
dc.identifier.eissn2045-2322
rioxxterms.typeJournal Article/Reviewen
pubs.funder-project-idEPSRC (EP/K039520/1)


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Attribution 4.0 International
Except where otherwise noted, this item's licence is described as Attribution 4.0 International