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dc.contributor.authorAljuraiban, Ghadeer
dc.contributor.authorChan, Queenie
dc.contributor.authorGibson, Rachel
dc.contributor.authorStamler, Jeremiah
dc.contributor.authorDaviglus, Martha L
dc.contributor.authorDyer, Alan R
dc.contributor.authorMiura, Katsuyuki
dc.contributor.authorWu, Yangfeng
dc.contributor.authorUeshima, Hirotsugu
dc.contributor.authorZhao, Liancheng
dc.contributor.authorVan Horn, Linda
dc.contributor.authorElliott, Paul
dc.contributor.authorOude Griep, Linda
dc.contributor.authorINTERMAP Research Group
dc.date.accessioned2020-10-20T23:30:13Z
dc.date.available2020-10-20T23:30:13Z
dc.date.issued2020-12
dc.identifier.issn2516-5542
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/311723
dc.description.abstractBACKGROUND: Plant-based diets are associated with a lower risk of cardiovascular diseases; however, little is known how the healthiness of the diet may be associated with blood pressure (BP). We aimed to modify three plant -based diet indices: overall plant-based diet index (PDI), healthy PDI (hPDI), and unhealthy PDI (uPDI) according to country-specific dietary guidelines to enable use across populations with diverse dietary patterns - and assessed their associations with BP. DESIGN: We used cross-sectional data including 4,680 men and women ages 40-59y in Japan, China, the United Kingdom, and the United States from the INTERnational study on MAcro/micronutrients and blood Pressure (INTERMAP). During four visits, eight BP measurements, and four 24-h dietary recalls were collected. Multivariable regression coefficients were estimated, pooled, weighted, and adjusted extensively for lifestyle/dietary confounders. RESULTS: Modified PDI was not associated with BP. Consumption of hPDI higher by 1SD was inversely associated with systolic (-0.82 mm Hg;95% CI:-1.32,-0.49) and diastolic BP (-0.49 mm Hg; 95% CI:-0.91, -0.28). In contrast, consumption of an uPDI was directly associated with systolic (0.77 mm Hg;95% CI:0.30,1.20). Significant associations between hPDI with BP were attenuated with separate adjustment for vegetables and whole grains; associations between uPDI and BP were attenuated after adjustment for refined grains, sugar-sweetened beverages, and meat. CONCLUSION: An hPDI is associated with lower BP while a uPDI is adversely related to BP. Plant-based diets rich in vegetables and whole grains and limited in refined grains, sugar-sweetened beverages, and total meat may contribute to these associations. In addition to current guidelines, the nutritional quality of consumed plant foods is as important as limiting animal-based components. TRIAL REGISTRATION NUMBER: The observational INTERMAP study was registered at www.clinicaltrials.gov as NCT00005271.
dc.format.mediumElectronic-eCollection
dc.languageeng
dc.publisherBMJ
dc.rightsAttribution-NonCommercial 4.0 International
dc.rights.urihttps://creativecommons.org/licenses/by-nc/4.0/
dc.subjectINTERMAP Research Group
dc.titleAssociation between plant-based diets and blood pressure in the INTERMAP study.
dc.typeArticle
prism.endingPage142
prism.issueIdentifier2
prism.publicationDate2020
prism.publicationNameBMJ Nutr Prev Health
prism.startingPage133
prism.volume3
dc.identifier.doi10.17863/CAM.58813
dcterms.dateAccepted2020-05-28
rioxxterms.versionofrecord10.1136/bmjnph-2020-000077
rioxxterms.versionVoR
rioxxterms.licenseref.urihttp://www.rioxx.net/licenses/all-rights-reserved
rioxxterms.licenseref.startdate2020-12
dc.contributor.orcidAljuraiban, Ghadeer [0000-0002-4866-5461]
dc.contributor.orcidOude Griep, Linda [0000-0001-7697-7473]
dc.identifier.eissn2516-5542
rioxxterms.typeJournal Article/Review
pubs.funder-project-idCambridge University Hospitals NHS Foundation Trust (CUH) (146281)
pubs.funder-project-idNational Institute for Health Research (NIHRDH-IS-BRC-1215-20014)
cam.issuedOnline2020-07-08


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Attribution-NonCommercial 4.0 International
Except where otherwise noted, this item's licence is described as Attribution-NonCommercial 4.0 International