Living with our machines: Towards a more sustainable future
Accepted version
Peer-reviewed
Repository URI
Repository DOI
Change log
Authors
Ley, SV
Chen, Y
Fitzpatrick, DE
May, OS
Abstract
© 2020 Elsevier B.V. With illustrative examples from our laboratories, we make the case for how our digital and machine-based world is impacting on the assembly of our functional molecules in a more sustainable fashion. Our equipment today is better able to deliver efficiencies through labour-saving methods, optimisation and scale-up, helping to minimise solvent usage, improve reaction telescoping and enhance other principles for process intensification. The machinery gives us confidence in safely handling reactive gases, exotherms and the other potentially hazardous events through remote control methods. Continuous flow chemistry processing plays a central role in delivering on this new holistic systems approach to synthesis.
Description
Keywords
Machine learning, Flow chemistry, Reactive gases.
Journal Title
Current Opinion in Green and Sustainable Chemistry
Conference Name
Journal ISSN
2452-2236
Volume Title
25
Publisher
Elsevier BV
Publisher DOI
Rights
All rights reserved
Sponsorship
European Commission Horizon 2020 (H2020) Future and Emerging Technologies (FET) (737266)
Y.C. thanks Pfizer for funding the postdoctoral fellowship. We thank the American Chemical Society through the Arthur C. Cope Fund (award to SVL). The authors also gratefully acknowledge financial support from H2020-FETOPEN-2016-2017 programe of European commission (SVL, DEF; grant agreement number: 737266-ONE FLOW).