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dc.contributor.authorBane, Octavia
dc.contributor.authorMendichovszky, Iosif A.
dc.contributor.authorMilani, Bastien
dc.contributor.authorDekkers, Ilona A.
dc.contributor.authorDeux, Jean-Francois
dc.contributor.authorEckerbom, Per
dc.contributor.authorGrenier, Nicolas
dc.contributor.authorHall, Michael E.
dc.contributor.authorInoue, Tsutomu
dc.contributor.authorLaustsen, Christoffer
dc.contributor.authorLerman, Lilach O.
dc.contributor.authorLiu, Chunlei
dc.contributor.authorMorrell, Glen
dc.contributor.authorPedersen, Michael
dc.contributor.authorPruijm, Menno
dc.contributor.authorSadowski, Elizabeth A.
dc.contributor.authorSeeliger, Erdmann
dc.contributor.authorSharma, Kanishka
dc.contributor.authorThoeny, Harriet
dc.contributor.authorVermathen, Peter
dc.contributor.authorWang, Zhen J.
dc.contributor.authorSerafin, Zbigniew
dc.contributor.authorZhang, Jeff L.
dc.contributor.authorFrancis, Susan T.
dc.contributor.authorSourbron, Steven
dc.contributor.authorPohlmann, Andreas
dc.contributor.authorFain, Sean B.
dc.contributor.authorPrasad, Pottumarthi V.
dc.date.accessioned2020-11-24T16:22:00Z
dc.date.available2020-11-24T16:22:00Z
dc.date.issued2019-11-25
dc.date.submitted2019-08-05
dc.identifier.citationMagnetic Resonance Materials in Physics, Biology and Medicine, volume 33, issue 1, page 199-215
dc.identifier.issn0968-5243
dc.identifier.others10334-019-00802-x
dc.identifier.other802
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/313267
dc.description.abstractAbstract: Harmonization of acquisition and analysis protocols is an important step in the validation of BOLD MRI as a renal biomarker. This harmonization initiative provides technical recommendations based on a consensus report with the aim to move towards standardized protocols that facilitate clinical translation and comparison of data across sites. We used a recently published systematic review paper, which included a detailed summary of renal BOLD MRI technical parameters and areas of investigation in its supplementary material, as the starting point in developing the survey questionnaires for seeking consensus. Survey data were collected via the Delphi consensus process from 24 researchers on renal BOLD MRI exam preparation, data acquisition, data analysis, and interpretation. Consensus was defined as ≥ 75% unanimity in response. Among 31 survey questions, 14 achieved consensus resolution, 12 showed clear respondent preference (65–74% agreement), and 5 showed equal (50/50%) split in opinion among respondents. Recommendations for subject preparation, data acquisition, processing and reporting are given based on the survey results and review of the literature. These technical recommendations are aimed towards increased inter-site harmonization, a first step towards standardization of renal BOLD MRI protocols across sites. We expect this to be an iterative process updated dynamically based on progress in the field.
dc.languageen
dc.publisherSpringer International Publishing
dc.rightsAttribution 4.0 International (CC BY 4.0)en
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/en
dc.subjectReview
dc.subjectBOLD MRI
dc.subjectKidney
dc.subjectImaging
dc.subjectBiomarkers
dc.subjectStandardization
dc.subjectConsensus
dc.titleConsensus-based technical recommendations for clinical translation of renal BOLD MRI
dc.typeArticle
dc.date.updated2020-11-24T16:22:00Z
dc.identifier.doi10.17863/CAM.60372
dcterms.dateAccepted2019-10-22
rioxxterms.versionofrecord10.1007/s10334-019-00802-x
rioxxterms.versionVoR
rioxxterms.licenseref.urihttp://creativecommons.org/licenses/by/4.0/
dc.contributor.orcidBane, Octavia [0000-0003-1315-5848]
dc.identifier.eissn1352-8661
pubs.funder-project-idNational Institute of Diabetes and Digestive and Kidney Diseases (1F32DK109591, R01 DK093793, R01 DK106557)
pubs.funder-project-idInnovative Medicines Initiative (115974, 115974)
pubs.funder-project-idDeutsche Forschungsgemeinschaft (Collaborative Research Centre SFB 1365 Renoprotection, Collaborative Research Centre SFB 1365 Renoprotection)
pubs.funder-project-idSchweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (320030-169191, NIZCOZO_177140/1)
pubs.funder-project-idMedical Research Council (MR/R02264X/1, MR/R02264X/1, MR/R02264X/1)
pubs.funder-project-idEuropean Cooperation in Science and Technology (Action CA 16103)


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Attribution 4.0 International (CC BY 4.0)
Except where otherwise noted, this item's licence is described as Attribution 4.0 International (CC BY 4.0)