Show simple item record

dc.contributor.authorIandolo, Donata
dc.contributor.authorSheard, Jonathan
dc.contributor.authorLevy, Galit Karavitas
dc.contributor.authorPitsalidis, Charalampos
dc.contributor.authorTan, Ellasia
dc.contributor.authorDennis, Anthony
dc.contributor.authorKim, Ji-Seon
dc.contributor.authorMarkaki, Athina E.
dc.contributor.authorWidera, Darius
dc.contributor.authorOwens, Róisín M.
dc.date.accessioned2020-12-03T16:28:16Z
dc.date.available2020-12-03T16:28:16Z
dc.date.issued2020-09-20
dc.date.submitted2019-11-27
dc.identifier.issn2159-6859
dc.identifier.otherart21
dc.identifier.other10010179
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/314457
dc.description.abstractAbstract: Osteoporosis is a skeletal disease characterized by bone loss and bone microarchitectural deterioration. The combination of smart materials and stem cells represents a new therapeutic approach. In the present study, highly porous scaffolds are prepared by combining the conducting polymer PEDOT:PSS with collagen type I, the most abundant protein in bone. The inclusion of collagen proves to be an effective way to modulate their mechanical properties and it induces an increase in scaffolds’ electrochemical impedance. The biomimetic scaffolds support neural crest-derived stem cell osteogenic differentiation, with no need for scaffold pre-conditioning contrarily to other reports.
dc.languageen
dc.publisherSpringer International Publishing
dc.rightsAttribution 4.0 International (CC BY 4.0)en
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/en
dc.subjectResearch Letter
dc.titleBiomimetic and electroactive 3D scaffolds for human neural crest-derived stem cell expansion and osteogenic differentiation
dc.typeArticle
dc.date.updated2020-12-03T16:28:14Z
prism.endingPage187
prism.issueIdentifier1
prism.publicationNameMRS Communications
prism.startingPage179
prism.volume10
dc.identifier.doi10.17863/CAM.61561
dcterms.dateAccepted2020-01-10
rioxxterms.versionofrecord10.1557/mrc.2020.10
rioxxterms.versionVoR
rioxxterms.licenseref.urihttp://creativecommons.org/licenses/by/4.0/
dc.identifier.eissn2159-6867


Files in this item

Thumbnail
Thumbnail
Thumbnail

This item appears in the following Collection(s)

Show simple item record

Attribution 4.0 International (CC BY 4.0)
Except where otherwise noted, this item's licence is described as Attribution 4.0 International (CC BY 4.0)