Assessing the global threat from Zika virus.
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Peer-reviewed
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Abstract
First discovered in 1947, Zika virus (ZIKV) infection remained a little-known tropical disease until 2015, when its apparent association with a considerable increase in the incidence of microcephaly in Brazil raised alarms worldwide. There is limited information on the key factors that determine the extent of the global threat from ZIKV infection and resulting complications. Here, we review what is known about the epidemiology, natural history, and public health effects of ZIKV infection, the empirical basis for this knowledge, and the critical knowledge gaps that need to be filled.
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Keywords
Animals, Biomedical Research, Brazil, Culex, Drug Design, Female, Global Health, Humans, Incidence, Microcephaly, Phylogeny, Pregnancy, Pregnancy Complications, Infectious, Public Health, Zika Virus, Zika Virus Infection
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Science
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0036-8075
1095-9203
1095-9203
Volume Title
353
Publisher
AAAS
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