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Cancer Screening, Surrogates of Survival, and the Soma.

Accepted version
Peer-reviewed

Type

Article

Change log

Authors

DeGregori, James 
Sasieni, Peter 
Swanton, Charles 

Abstract

Screening leads to meaningful reductions in deaths from cancers. However, reductions in all-cause mortality (ACM) are harder to demonstrate. Failure to demonstrate ACM benefit should not diminish advances in cancer screening. We consider how co-morbidities related to an aging and damaged soma can hinder achievement of ACM benefit.

Description

Keywords

Aging, Cause of Death, Early Detection of Cancer, Neoplasms, Risk Assessment, Risk Factors, Smoking, Survival Analysis, Survival Rate

Journal Title

Cancer Cell

Conference Name

Journal ISSN

1535-6108
1878-3686

Volume Title

38

Publisher

Cell Press