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dc.contributor.authorJensen, Melanie P
dc.contributor.authorRowe, James B
dc.contributor.authorAllinson, Kieren SJ
dc.date.accessioned2021-01-29T00:30:45Z
dc.date.available2021-01-29T00:30:45Z
dc.date.issued2021-05
dc.identifier.issn0722-5091
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/316845
dc.description.abstractWe present a case report of a patient with a history of renal cell carcinoma in which corticobasal syndrome had been diagnosed ante-mortem. However, distinguishing features of corticobasal degeneration pathology were absent at post-mortem. Instead, neuropathological examination revealed features consistent with the patient's history of renal cell carcinoma: micrometastatic renal cell carcinoma in cerebellar and cerebral white matter, including within the gyral white matter of the primary motor and somatosensory cortices. There was also Purkinje cell loss and mild lymphocytic inflammation in the cerebellum, but the significance of this was unclear. A number of "corticobasal degeneration mimics" have been described in the literature, but micrometastatic carcinoma causing corticobasal syndrome is a novel finding. This case expands the range of clinical disorders which may mimic corticobasal degeneration to include micrometastatic carcinoma.
dc.format.mediumPrint
dc.languageeng
dc.publisherDustri-Verlgag Dr. Karl Feistle
dc.rightsAll rights reserved
dc.titleA case report of metastatic renal cell carcinoma causing corticobasal syndrome.
dc.typeArticle
prism.endingPage164
prism.issueIdentifier3
prism.publicationDate2021
prism.publicationNameClin Neuropathol
prism.startingPage160
prism.volume40
dc.identifier.doi10.17863/CAM.63961
dcterms.dateAccepted2021-04-21
rioxxterms.versionofrecord10.5414/NP301343
rioxxterms.versionAM
rioxxterms.licenseref.urihttp://www.rioxx.net/licenses/all-rights-reserved
rioxxterms.licenseref.startdate2021-05
dc.contributor.orcidRowe, James [0000-0001-7216-8679]
rioxxterms.typeJournal Article/Review
pubs.funder-project-idWellcome Trust (103838/Z/14/Z)
pubs.funder-project-idCambridge University Hospitals NHS Foundation Trust (CUH) (146281)
pubs.funder-project-idMedical Research Council (MC_U105597119)
pubs.funder-project-idMedical Research Council (MC_UU_00005/12)
rioxxterms.freetoread.startdate2022-01-12


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