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dc.contributor.authorAbbasi, Nooshin
dc.contributor.authorDuncan, John
dc.contributor.authorRajimehr, Reza
dc.date.accessioned2021-02-04T16:26:32Z
dc.date.available2021-02-04T16:26:32Z
dc.date.issued2020-02-05
dc.date.submitted2019-06-24
dc.identifier.others41467-020-14610-8
dc.identifier.other14610
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/317166
dc.descriptionFunder: RCUK | Medical Research Council (MRC); doi: https://doi.org/10.13039/501100000265
dc.description.abstractAbstract: Human visual cortex contains discrete areas that respond selectively to specific object categories such as faces, bodies, and places. A long-standing question is whether these areas are shaped by genetic or environmental factors. To address this question, here we analyzed functional MRI data from an unprecedented number (n = 424) of monozygotic (MZ) and dizygotic (DZ) twins. Category-selective maps were more identical in MZ than DZ twins. Within each category-selective area, distinct subregions showed significant genetic influence. Structural MRI analysis revealed that the ‘genetic voxels’ were predominantly located in regions with higher cortical curvature (gyral crowns in face areas and sulcal fundi in place areas). Moreover, we found that cortex was thicker and more myelinated in genetic voxels of face areas, while it was thinner and less myelinated in genetic voxels of place areas. This double dissociation suggests a differential development of face and place areas in cerebral cortex.
dc.languageen
dc.publisherNature Publishing Group UK
dc.rightsAttribution 4.0 International (CC BY 4.0)en
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/en
dc.subjectArticle
dc.subject/631/208/1515
dc.subject/631/378/2649
dc.subject/631/378/2613/2616
dc.subject/59/36
dc.subjectarticle
dc.titleGenetic influence is linked to cortical morphology in category-selective areas of visual cortex
dc.typeArticle
dc.date.updated2021-02-04T16:26:32Z
prism.issueIdentifier1
prism.publicationNameNature Communications
prism.volume11
dc.identifier.doi10.17863/CAM.64277
dcterms.dateAccepted2020-01-22
rioxxterms.versionofrecord10.1038/s41467-020-14610-8
rioxxterms.versionVoR
rioxxterms.licenseref.urihttp://creativecommons.org/licenses/by/4.0/
dc.contributor.orcidRajimehr, Reza [0000-0002-3248-3305]
dc.identifier.eissn2041-1723


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Attribution 4.0 International (CC BY 4.0)
Except where otherwise noted, this item's licence is described as Attribution 4.0 International (CC BY 4.0)