The interplay between ESCRT and viral factors in the envel- 2
Accepted version
Peer-reviewed
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Repository DOI
Change log
Authors
Meng, Bo
Lever, Andrew
Abstract
Viruses are obligate parasites that reply on host cellular factors to replicate and spread. The endosomal sorting complex required for transport (ESCRT) system, classically associated with sorting and downgrading surface proteins, is one of such host machineries hijacked by viruses across diverse families. Knowledge gained from research into ESCRT and viruses has in turn greatly advanced our understanding of many other cellular functions in which the ESCRT pathway is involved, e.g., cytokinesis. This review highlights the interplay between the ESCRT pathway and the viral factors of enveloped viruses with a special emphasis on retroviruses.
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Journal Title
Viruses
Conference Name
Journal ISSN
1999-4915
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Publisher
MDPI AG
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All rights reserved
Sponsorship
Medical Research Council (MR/N022939/1)
Microbiology Society (GA000985) and the UK Medical Research Council (MRC, MR/N0229939/1).