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dc.contributor.authorPapoutsaki, Marianthi-Vasiliki
dc.contributor.authorAllen, Clare
dc.contributor.authorGiganti, Francesco
dc.contributor.authorAtkinson, David
dc.contributor.authorDickinson, Louise
dc.contributor.authorGoodman, Jacob
dc.contributor.authorSaunders, Helen
dc.contributor.authorBarrett, Tristan
dc.contributor.authorPunwani, Shonit
dc.date.accessioned2021-04-20T16:37:23Z
dc.date.available2021-04-20T16:37:23Z
dc.date.issued2021-04-20
dc.date.submitted2020-12-16
dc.identifier.others13244-021-00990-y
dc.identifier.other990
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/321346
dc.descriptionFunder: North East London Cancer Alliance
dc.descriptionFunder: KCL/UCL Comprehensive Cancer Imaging Centre
dc.descriptionFunder: UCLH Biomedical Research Centre
dc.description.abstractAbstract: Objectives: National guidelines recommend prostate multiparametric (mp) MRI in men with suspected prostate cancer before biopsy. In this study, we explore prostate mpMRI protocols across 14 London hospitals and determine whether standardisation improves diagnostic quality. Methods: An MRI physicist facilitated mpMRI set-up across several regional hospitals, working together with experienced uroradiologists who judged diagnostic quality. Radiologists from the 14 hospitals participated in the assessment and optimisation of prostate mpMRI image quality, assessed according to both PiRADSv2 recommendations and on the ability to “rule in” and/or “rule out” prostate cancer. Image quality and sequence parameters of representative mpMRI scans were evaluated across 23 MR scanners. Optimisation visits were performed to improve image quality, and 2 radiologists scored the image quality pre- and post-optimisation. Results: 20/23 mpMRI protocols, consisting of 111 sequences, were optimised by modifying their sequence parameters. Pre-optimisation, only 15% of T2W images were non-diagnostic, whereas 40% of ADC maps, 50% of high b-value DWI and 41% of DCE-MRI were considered non-diagnostic. Post-optimisation, the scores were increased with 80% of ADC maps, 74% of high b-value DWI and 88% of DCE-MRI to be partially or fully diagnostic. T2W sequences were not optimised, due to their higher baseline quality scores. Conclusions: Targeted intervention at a regional level can improve the diagnostic quality of prostate mpMRI protocols, with implications for improving prostate cancer detection rates and targeted biopsies.
dc.languageen
dc.publisherSpringer International Publishing
dc.subjectOriginal Article
dc.subjectMultiparametric magnetic resonance imaging
dc.subjectClinical protocols
dc.subjectProstatic neoplasms
dc.subjectDiffusion
dc.subjectContrast media
dc.titleStandardisation of prostate multiparametric MRI across a hospital network: a London experience
dc.typeArticle
dc.date.updated2021-04-20T16:37:22Z
prism.issueIdentifier1
prism.publicationNameInsights into Imaging
prism.volume12
dc.identifier.doi10.17863/CAM.68467
dcterms.dateAccepted2021-03-22
rioxxterms.versionofrecord10.1186/s13244-021-00990-y
rioxxterms.versionVoR
rioxxterms.licenseref.urihttp://creativecommons.org/licenses/by/4.0/
dc.contributor.orcidPunwani, Shonit [0000-0001-9865-0260]
dc.identifier.eissn1869-4101


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