Synthetic Enzyme‐Catalyzed CO 2 Fixation Reactions
Aleku, Godwin A.
Roberts, George W.
Titchiner, Gabriel R.
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Aleku, G. A., Roberts, G. W., Titchiner, G. R., & Leys, D. (2021). Synthetic Enzyme‐Catalyzed CO 2 Fixation Reactions. ChemSusChem, 14 (8), 1781-1804. https://doi.org/10.1002/cssc.202100159
Abstract: In recent years, (de)carboxylases that catalyze reversible (de)carboxylation have been targeted for application as carboxylation catalysts. This has led to the development of proof‐of‐concept (bio)synthetic CO2 fixation routes for chemical production. However, further progress towards industrial application has been hampered by the thermodynamic constraint that accompanies fixing CO2 to organic molecules. In this Review, biocatalytic carboxylation methods are discussed with emphases on the diverse strategies devised to alleviate the inherent thermodynamic constraints and their application in synthetic CO2‐fixation cascades.
Review, Reviews, biocatalysis, carboxylation, cascade reactions, CO2 fixation, enzymes
ERC (pre-FAB 695013)
External DOI: https://doi.org/10.1002/cssc.202100159
This record's URL: https://www.repository.cam.ac.uk/handle/1810/321459