Climate change is having widespread and, in some places, devastating impacts on people and their livelihoods, compromising human health, agriculture and food security, and provoking migration and conflict. This briefing connects the structural disadvantage experienced by many young people in low- and middle-income countries, to the upheaval, uncertainty and stress caused by climate change. To facilitate the involvement of young people in framing and responding to climate change, the briefing draws upon the study of marginalised young people from the remote Ugandan district of Karamoja, to give a voice to youth experiences, needs, and ideas for change.