Development of High-Throughput Screening Platforms for the Directed Evolution and Design of CRISPR-Associated Nucleases Towards Enhanced Genome Editing
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Type
Thesis
Change log
Authors
Herger, Michael
Abstract
[Restricted]
Description
Date
2020-01-01
Advisors
Hollfelder, Florian
Snaith, Michael
Snaith, Michael
Keywords
CRISPR, Cas9, Cas12a, Directed Evolution, Protein Engineering, PAM, Microfluidics
Qualification
Doctor of Philosophy (PhD)
Awarding Institution
University of Cambridge
Rights
Sponsorship
MedImmune Studentship: "Mechanism and Directed Evolution of Genome-Editing Enzymes" (RG75909)