Human embryo research, stem cell-derived embryo models and in vitro gametogenesis: Considerations leading to the revised ISSCR guidelines.
Accepted version
Peer-reviewed
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Repository DOI
Change log
Authors
Abstract
The ISSCR Guidelines for Stem Cell Research and Clinical Translation were last revised in 2016. Since then, rapid progress has been made in research areas related to in vitro culture of human embryos, creation of stem cell-based embryo models, and in vitro gametogenesis. Therefore, a working group of international experts was convened to review the oversight process and provide an update to the guidelines. This report captures the discussion and summarizes the major recommendations made by this working group, with a specific emphasis on updating the categories of review and engagement with the specialized scientific and ethical oversight process.
Description
Keywords
embryo models, embryo research, gametoogensis, guidelines, Embryo Research, Embryo, Mammalian, Embryonic Stem Cells, Gametogenesis, Humans, Models, Biological, Practice Guidelines as Topic, Societies, Scientific, Stem Cell Research
Journal Title
Stem Cell Reports
Conference Name
Journal ISSN
2213-6711
2213-6711
2213-6711
Volume Title
16
Publisher
Elsevier BV
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Rights
All rights reserved
Sponsorship
Wellcome Trust (209475/Z/17/Z)
Medical Research Council (MR/P009948/1)
BBSRC (BB/T01346X/1)
Wellcome Trust (221856/Z/20/Z)
Medical Research Council (MR/P009948/1)
BBSRC (BB/T01346X/1)
Wellcome Trust (221856/Z/20/Z)