Immature acute leukaemias: lessons from the haematopoietic roadmap
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Peer-reviewed
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Abstract
It is essential to relate the biology of acute leukaemia to normal blood cell development. In this review, we discuss how modern models of haematopoiesis might inform approaches to diagnosis and management of immature leukaemias, with a specific focus on T‐lymphoid and myeloid cases. In particular, we consider whether next‐generation analytical tools could provide new perspectives that could improve our understanding of immature blood cancer biology.
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Funder: European Hematology Association; Id: http://dx.doi.org/10.13039/100008594
Funder: La Ligue contre le cancer; Id: http://dx.doi.org/10.13039/501100004099
Funder: Wellcome Trust; Id: http://dx.doi.org/10.13039/100004440
Funder: Association Laurette Fugain; Id: http://dx.doi.org/10.13039/100007394
Funder: Biotechnology and Biological Sciences Research Council; Id: http://dx.doi.org/10.13039/501100000268
Funder: Assistance Publique ‐ Hôpitaux de Paris; Id: http://dx.doi.org/10.13039/501100002738
Funder: Medical Research Council; Id: http://dx.doi.org/10.13039/501100000265
Funder: Institut National Du Cancer; Id: http://dx.doi.org/10.13039/501100006364
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1742-4658
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Irish Cancer Society (CRF20JON)