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dc.contributor.authorGong, Hengfen
dc.contributor.authorZhang, Yingying
dc.contributor.authorRen, Qihuan
dc.contributor.authorZhou, Zhirong
dc.contributor.authorZhou, Huijing
dc.contributor.authorSun, Xirong
dc.contributor.authorZhang, Chencheng
dc.contributor.authorVoon, Valerie
dc.contributor.authorZhao, Min
dc.contributor.authorYu, Shunying
dc.date.accessioned2021-09-25T15:39:05Z
dc.date.available2021-09-25T15:39:05Z
dc.date.issued2020-09-25
dc.date.submitted2020-03-10
dc.identifier.others12888-020-02843-2
dc.identifier.other2843
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/328530
dc.descriptionFunder: Guangci Professorship Program of Ruijin Hospital and Shanghai Jiao Tong University School of Medicine 2018 International and Hong Kong, Macao and Taiwan Regional Research Cooperation Project
dc.description.abstractAbstract: Background: The Obsessive Compulsive Drug Use Scale (OCDUS) measures the overall craving level within a period from a multidimensional perspective. However, no studies have addressed the validity of the new OCDUS factor structure, presented in 2016, in China. Additionally, there is lack of evidence on the interaction among risk factors for relapse. We aimed to assess the psychometric properties of the scores of the Chinese version of the OCDUS in patients with heroin dependence receiving methadone maintenance treatment (MMT). Further, we aimed to assess the correlations of the OCDUS scores with withdrawal symptoms, depression, anxiety, and nicotine dependence. Methods: We enrolled 113 adults (age 32–64 years) and administered them with the OCDUS, Subjective Opioid Withdrawal Scale (SOWS), Beck Depression Inventory-II (BDI-II), State-Trait Anxiety Inventory (STAI), and Fagerstrom Test for Nicotine Dependence (FTND). Results: Exploratory factor analysis identified a 3-dimensional component that included “Frequency of craving,” “Inference of heroin,” and “Control of heroin.” These factors showed acceptable internal consistency, adequate item-total correlations, and significant item-subscale correlations. There was no correlation between the OCUDS scores and age, education, duration of receiving MMT, and MMT dosages. However, there was a significant correlation between the OCDUS total scores and the SOWS, STAI, BDI-II, and FTND scores. The scores of all the subscales were associated with the SOWS scores; further, the scores of the first two subscales were associated with BDI-II scores while only the scores of the first subscale were associated with the FTND scores. Conclusions: Our findings support the reliability and structure validity of the OCDUS scores. Heroin craving, withdrawal symptoms, negative emotions, and nicotine dependence, which are considered as risk factors for heroin relapse, might interact with each other. There is a need for further studies on the underlying mechanism of these clinical phenomena.
dc.languageen
dc.publisherBioMed Central
dc.subjectResearch Article
dc.subjectSubstance-related disorders, addiction and impulse control
dc.subjectObsessive compulsive drug use scale
dc.subjectMethadone maintenance treatment
dc.subjectCraving
dc.subjectNicotine dependence
dc.subjectHeroin
dc.titleThe Chinese version of obsessive compulsive drug use scale: validation in outpatient methadone maintenance treatment program
dc.typeArticle
dc.date.updated2021-09-25T15:39:04Z
prism.issueIdentifier1
prism.publicationNameBMC Psychiatry
prism.volume20
dc.identifier.doi10.17863/CAM.75978
dcterms.dateAccepted2020-08-30
rioxxterms.versionofrecord10.1186/s12888-020-02843-2
rioxxterms.versionVoR
rioxxterms.licenseref.urihttp://creativecommons.org/licenses/by/4.0/
dc.identifier.eissn1471-244X
pubs.funder-project-idShanghai Pudong New District Health and Family Planning Commission Key Discipline Construction Fund Project (PWZxk2017-29)
pubs.funder-project-idShanghai Municipal Science and Technology Major Project (2018SHZDZX05)
pubs.funder-project-idShanghai Clinical Research Center for Mental Health (19MC1911100)


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