Regulation of chaperone activity in the endoplasmic reticulum

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Authors
Preissler, S
Publication Date
2020-11
Journal Title
BioSpektrum
ISSN
0947-0867
Publisher
Springer Science and Business Media LLC
Volume
26
Issue
6
Pages
612-614
Language
de
Type
Article
This Version
VoR
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Citation
Preissler, S. (2020). Regulation of chaperone activity in the endoplasmic reticulum. BioSpektrum, 26 (6), 612-614. https://doi.org/10.1007/s12268-020-1455-6
Abstract
<jats:title>Abstract</jats:title><jats:p>Maintenance of protein homeostasis depends on cellular stress response pathways that mediate adaptive changes in gene expression. In the endoplasmic reticulum additional mechanisms adjust the availability of the abundant Hsp70-type chaperone, BiP, during short-term fluctuations in the unfolded protein load. Here, recent insights into the regulation of BiP by incorporation into inactive oligomers and reversible AMPylation are discussed.</jats:p>
Keywords
Wissenschaft
Identifiers
s12268-020-1455-6, 1455
External DOI: https://doi.org/10.1007/s12268-020-1455-6
This record's URL: https://www.repository.cam.ac.uk/handle/1810/329487
Rights
Licence:
http://creativecommons.org/licenses/by/4.0/
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