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dc.contributor.authorHempel, Elisabeth
dc.contributor.authorWestbury, Michael V
dc.contributor.authorGrau, José H
dc.contributor.authorTrinks, Alexandra
dc.contributor.authorPaijmans, Johanna
dc.contributor.authorKliver, Sergei
dc.contributor.authorBarlow, Axel
dc.contributor.authorMayer, Frieder
dc.contributor.authorMüller, Johannes
dc.contributor.authorChen, Lei
dc.contributor.authorKoepfli, Klaus-Peter
dc.contributor.authorHofreiter, Michael
dc.contributor.authorBibi, Faysal
dc.date.accessioned2021-10-27T23:30:19Z
dc.date.available2021-10-27T23:30:19Z
dc.date.issued2021-08-11
dc.identifier.issn2073-4425
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/329958
dc.description.abstractSince the 19th century, the addax (Addax nasomaculatus) has lost approximately 99% of its former range. Along with its close relatives, the blue antelope (Hippotragus leucophaeus) and the scimitar-horned oryx (Oryx dammah), the addax may be the third large African mammal species to go extinct in the wild in recent times. Despite this, the evolutionary history of this critically endangered species remains virtually unknown. To gain insight into the population history of the addax, we used hybridization capture to generate ten complete mitochondrial genomes from historical samples and assembled a nuclear genome. We found that both mitochondrial and nuclear diversity are low compared to other African bovids. Analysis of mitochondrial genomes revealed a most recent common ancestor ~32 kya (95% CI 11-58 kya) and weak phylogeographic structure, indicating that the addax likely existed as a highly mobile, panmictic population across its Sahelo-Saharan range in the past. PSMC analysis revealed a continuous decline in effective population size since ~2 Ma, with short intermediate increases at ~500 and ~44 kya. Our results suggest that the addax went through a major bottleneck in the Late Pleistocene, remaining at low population size prior to the human disturbances of the last few centuries.
dc.format.mediumElectronic
dc.languageeng
dc.publisherMDPI AG
dc.rightsAttribution 4.0 International
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.titleDiversity and Paleodemography of the Addax (Addax nasomaculatus), a Saharan Antelope on the Verge of Extinction.
dc.typeArticle
prism.issueIdentifier8
prism.publicationDate2021
prism.publicationNameGenes (Basel)
prism.volume12
dc.identifier.doi10.17863/CAM.77402
dcterms.dateAccepted2021-08-08
rioxxterms.versionofrecord10.3390/genes12081236
rioxxterms.versionVoR
rioxxterms.licenseref.urihttp://www.rioxx.net/licenses/all-rights-reserved
rioxxterms.licenseref.startdate2021-08-11
dc.contributor.orcidHempel, Elisabeth [0000-0002-0089-8741]
dc.contributor.orcidWestbury, Michael V [0000-0003-0478-3930]
dc.contributor.orcidPaijmans, Johanna [0000-0002-1938-7052]
dc.contributor.orcidBarlow, Axel [0000-0002-5532-9458]
dc.contributor.orcidKoepfli, Klaus-Peter [0000-0001-7281-0676]
dc.contributor.orcidHofreiter, Michael [0000-0003-0441-4705]
dc.identifier.eissn2073-4425
rioxxterms.typeJournal Article/Review
cam.issuedOnline2021-08-11


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Attribution 4.0 International
Except where otherwise noted, this item's licence is described as Attribution 4.0 International