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dc.contributor.authorÖzpolat, B Duygu
dc.contributor.authorRandel, Nadine
dc.contributor.authorWilliams, Elizabeth A
dc.contributor.authorBezares-Calderón, Luis Alberto
dc.contributor.authorAndreatta, Gabriele
dc.contributor.authorBalavoine, Guillaume
dc.contributor.authorBertucci, Paola Y
dc.contributor.authorFerrier, David E K
dc.contributor.authorGambi, Maria Cristina
dc.contributor.authorGazave, Eve
dc.contributor.authorHandberg-Thorsager, Mette
dc.contributor.authorHardege, Jörg
dc.contributor.authorHird, Cameron
dc.contributor.authorHsieh, Yu-Wen
dc.contributor.authorHui, Jerome
dc.contributor.authorMutemi, Kevin Nzumbi
dc.contributor.authorSchneider, Stephan Q
dc.contributor.authorSimakov, Oleg
dc.contributor.authorVergara, Hernando M
dc.contributor.authorVervoort, Michel
dc.contributor.authorJékely, Gáspár
dc.contributor.authorTessmar-Raible, Kristin
dc.contributor.authorRaible, Florian
dc.contributor.authorArendt, Detlev
dc.date.accessioned2021-10-30T01:12:09Z
dc.date.available2021-10-30T01:12:09Z
dc.date.issued2021-09-27
dc.identifier.issn2041-9139
dc.identifier.otherPMC8477482
dc.identifier.other34579780
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/330080
dc.descriptionFunder: RITMARE - Flag project
dc.descriptionFunder: Hibbitt Startup Funds
dc.descriptionFunder: PON-MODO project
dc.descriptionFunder: MARES Consortium
dc.descriptionFunder: ASSEMBLE
dc.description.abstractThe Nereid Platynereis dumerilii (Audouin and Milne Edwards (Annales des Sciences Naturelles 1:195-269, 1833) is a marine annelid that belongs to the Nereididae, a family of errant polychaete worms. The Nereid shows a pelago-benthic life cycle: as a general characteristic for the superphylum of Lophotrochozoa/Spiralia, it has spirally cleaving embryos developing into swimming trochophore larvae. The larvae then metamorphose into benthic worms living in self-spun tubes on macroalgae. Platynereis is used as a model for genetics, regeneration, reproduction biology, development, evolution, chronobiology, neurobiology, ecology, ecotoxicology, and most recently also for connectomics and single-cell genomics. Research on the Nereid started with studies on eye development and spiralian embryogenesis in the nineteenth and early twentieth centuries. Transitioning into the molecular era, Platynereis research focused on posterior growth and regeneration, neuroendocrinology, circadian and lunar cycles, fertilization, and oocyte maturation. Other work covered segmentation, photoreceptors and other sensory cells, nephridia, and population dynamics. Most recently, the unique advantages of the Nereid young worm for whole-body volume electron microscopy and single-cell sequencing became apparent, enabling the tracing of all neurons in its rope-ladder-like central nervous system, and the construction of multimodal cellular atlases. Here, we provide an overview of current topics and methodologies for P. dumerilii, with the aim of stimulating further interest into our unique model and expanding the active and vibrant Platynereis community.
dc.languageeng
dc.rightsAttribution 4.0 International
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.sourceessn: 2041-9139
dc.sourcenlmid: 101525836
dc.subjectAnnelida
dc.subjectEvo-devo
dc.subjectIntegrative Biology
dc.subjectSpiralia
dc.subjectMarine Model Species
dc.titleThe Nereid on the rise: Platynereis as a model system.
dc.typeArticle
dc.date.updated2021-10-30T01:12:08Z
prism.issueIdentifier1
prism.publicationNameEvoDevo
prism.volume12
dc.identifier.doi10.17863/CAM.77524
rioxxterms.versionofrecord10.1186/s13227-021-00180-3
rioxxterms.versionVoR
rioxxterms.licenseref.urihttps://creativecommons.org/licenses/by/4.0/
dc.contributor.orcidÖzpolat, B Duygu [0000-0002-1900-965X]
dc.contributor.orcidRandel, Nadine [0000-0002-7817-4137]
dc.contributor.orcidWilliams, Elizabeth A [0000-0003-3067-3137]
dc.contributor.orcidAndreatta, Gabriele [0000-0001-8857-7282]
dc.contributor.orcidBalavoine, Guillaume [0000-0003-0880-1331]
dc.contributor.orcidFerrier, David E K [0000-0003-3247-6233]
dc.contributor.orcidGambi, Maria Cristina [0000-0002-0168-776X]
dc.contributor.orcidGazave, Eve [0000-0002-4647-6640]
dc.contributor.orcidHandberg-Thorsager, Mette [0000-0002-3908-7233]
dc.contributor.orcidHardege, Jörg [0000-0002-7815-3969]
dc.contributor.orcidHird, Cameron [0000-0002-4631-9418]
dc.contributor.orcidHsieh, Yu-Wen [0000-0002-4500-5724]
dc.contributor.orcidMutemi, Kevin Nzumbi [0000-0002-6426-2363]
dc.contributor.orcidSchneider, Stephan Q [0000-0002-8981-7089]
dc.contributor.orcidSimakov, Oleg [0000-0002-3585-4511]
dc.contributor.orcidVervoort, Michel [0000-0002-5995-2140]
dc.contributor.orcidJékely, Gáspár [0000-0001-8496-9836]
dc.contributor.orcidTessmar-Raible, Kristin [0000-0002-8038-1741]
dc.contributor.orcidRaible, Florian [0000-0002-4515-6485]
pubs.funder-project-idNIGMS NIH HHS (1R35GM138008-01)
pubs.funder-project-idLigue Contre le Cancer (RS20/75-20)
pubs.funder-project-idDeutsche Forschungsgemeinschaft (TO563/7-1)
pubs.funder-project-idNational Institute of General Medical Sciences (1R35GM138008-01)
pubs.funder-project-idLABoratoires d'EXcellence ARCANE (ANR-11-LABX-0071)
pubs.funder-project-idNatural Environment Research Council (NE/T001577/1)
pubs.funder-project-idDivision of Integrative Organismal Systems (IOS-1455185)
pubs.funder-project-idBiotechnology and Biological Sciences Research Council (BB/T00990X/1)
pubs.funder-project-idLABoratoires d’EXcellence ARCANE (ANR-11-LABX-0071)
pubs.funder-project-idNational Science Foundation (1923429)
pubs.funder-project-idAcademia Sinica Career Development Award (AS-CDA-110-L02)
pubs.funder-project-idAustrian Science Fund FWF (Y413, I2972, P28970, P32190, F78)
pubs.funder-project-idUniversity of Vienna (Single-cell genomics of stem cells, Rhythms of Life)
pubs.funder-project-idHorizon 2020 Framework Programme (Grant Agreement 81995)
pubs.funder-project-idWellcome Trust (214337/Z/18/Z)
pubs.funder-project-idH2020 Marie Skłodowska-Curie Actions (838225, 766053)
pubs.funder-project-idAgence Nationale de la Recherche (ANR-16-CE91-0007, ANR-19-CE27-0027-02)
pubs.funder-project-idEuropean Research Council ((FP7/2007-2013) ERC Grant Agreement 260304, (FP7/2007-2013) ERC Grant Agreement 337011, (FP7/2007–2013) ERC Grant Agreement 337011, NeuralCellTypeEvo #788921, (FP7/2007–2013) ERC Grant Agreement 260304)
pubs.funder-project-idARC (PJA 20181208248)


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Attribution 4.0 International
Except where otherwise noted, this item's licence is described as Attribution 4.0 International