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dc.contributor.authorGeddes, Donna Tracy
dc.contributor.authorGridneva, Zoya
dc.contributor.authorPerrella, Sharon Lisa
dc.contributor.authorMitoulas, Leon Robert
dc.contributor.authorKent, Jacqueline Coral
dc.contributor.authorStinson, Lisa Faye
dc.contributor.authorLai, Ching Tat
dc.contributor.authorSakalidis, Vanessa
dc.contributor.authorTwigger, Alecia-Jane
dc.contributor.authorHartmann, Peter Edwin
dc.date.accessioned2021-10-30T01:13:42Z
dc.date.available2021-10-30T01:13:42Z
dc.date.issued2021-08-31
dc.identifier.issn2072-6643
dc.identifier.otherPMC8465002
dc.identifier.other34578947
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/330098
dc.description.abstractResearchers have recently called for human lactation research to be conceptualized as a biological framework where maternal and infant factors impacting human milk, in terms of composition, volume and energy content are studied along with relationships to infant growth, development and health. This approach allows for the development of evidence-based interventions that are more likely to support breastfeeding and lactation in pursuit of global breastfeeding goals. Here we summarize the seminal findings of our research programme using a biological systems approach traversing breast anatomy, milk secretion, physiology of milk removal with respect to breastfeeding and expression, milk composition and infant intake, and infant gastric emptying, culminating in the exploration of relationships with infant growth, development of body composition, and health. This approach has allowed the translation of the findings with respect to education, and clinical practice. It also sets a foundation for improved study design for future investigations in human lactation.
dc.languageeng
dc.publisherMDPI AG
dc.rightsAttribution 4.0 International
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.sourceessn: 2072-6643
dc.sourcenlmid: 101521595
dc.subjectBreast
dc.subjectLactation
dc.subjectMilk composition
dc.subjectHuman Milk
dc.subjectInfant Feeding
dc.subjectBreastfeeding
dc.title25 Years of Research in Human Lactation: From Discovery to Translation.
dc.typeArticle
dc.date.updated2021-10-30T01:13:41Z
prism.issueIdentifier9
prism.publicationNameNutrients
prism.volume13
dc.identifier.doi10.17863/CAM.77542
dcterms.dateAccepted2021-08-26
rioxxterms.versionofrecord10.3390/nu13093071
rioxxterms.versionVoR
rioxxterms.licenseref.urihttps://creativecommons.org/licenses/by/4.0/
dc.contributor.orcidGridneva, Zoya [0000-0001-6841-2958]
dc.contributor.orcidPerrella, Sharon Lisa [0000-0002-7727-7767]
dc.contributor.orcidLai, Ching Tat [0000-0002-9025-4922]
dc.contributor.orcidTwigger, Alecia-Jane [0000-0003-4361-817X]
dc.identifier.eissn2072-6643
pubs.funder-project-idMedela (University of Western Australia)
cam.issuedOnline2021-08-31


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Attribution 4.0 International
Except where otherwise noted, this item's licence is described as Attribution 4.0 International