Show simple item record

dc.contributor.authorColeman, Tim
dc.contributor.authorClark, Miranda
dc.contributor.authorWelch, Charlie
dc.contributor.authorWhitemore, Rachel
dc.contributor.authorLeonardi-Bee, Jo
dc.contributor.authorCooper, Sue
dc.contributor.authorHewitt, Catherine
dc.contributor.authorJones, Matthew
dc.contributor.authorSutton, Stephen
dc.contributor.authorWatson, Judith
dc.contributor.authorDaykin, Karen
dc.contributor.authorUssher, Michael
dc.contributor.authorParrott, Steve
dc.contributor.authorNaughton, Felix
dc.date.accessioned2021-11-05T11:30:00Z
dc.date.available2021-11-05T11:30:00Z
dc.date.issued2022-04
dc.date.submitted2021-02-23
dc.identifier.issn0965-2140
dc.identifier.otheradd15715
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/330327
dc.description.abstractAIMS: To test the efficacy of 'MiQuit', a tailored, self-help, text message stop smoking programme for pregnancy, as an adjunct to usual care (UC) for smoking cessation in pregnancy. DESIGN: Multicentre, open, two-arm, parallel-group, superiority randomised controlled trial (RCT) and a trial sequential analysis (TSA) meta-analysis combining trial findings with two previous ones. SETTING: Twenty-four English hospital antenatal clinics. PARTICIPANTS: A total of 1002 pregnant women who were ≥16 years old, were ≤25 weeks gestation and smoked ≥1 daily cigarette and accepted information on cessation with no requirement to set quit dates. INTERVENTIONS: UC or UC plus 'MiQuit': 12 weeks of tailored, smoking cessation text messages focussed on inducing and aiding cessation. MEASUREMENTS: Primary outcome: biochemically validated cessation between 4 weeks after randomisation and late pregnancy. SECONDARY OUTCOMES: shorter and non-validated abstinence periods, pregnancy outcomes and incremental cost-effectiveness ratios. FINDINGS: RCT: cessation was 5.19% (26/501) and 4.59% (23/501) in MiQuit and UC groups (adjusted odds ratio [adj OR] for quitting with MiQuit versus UC, 95% CI = 1.15 [0.65-2.04]); other abstinence findings were similar, with higher point estimates. Primary outcome ascertainment was 61.7% (309) and 67.3% (337) in MiQuit and UC groups with 71.1% (54/76) and 69.5% (41/59) abstinence validation rates, respectively. Pregnancy outcomes were similar and the incremental cost per quality-adjusted life year was -£1118 (95% CI = -£4806-£1911). More MiQuit group women reported making at least one quit attempt (adj OR [95% CI]) for making an attempt, 1.50 (1.07-2.09). TSA meta-analysis: this found no significant difference in prolonged abstinence between MiQuit and UC (pooled OR = 1.49, adjusted 95% CI = 0.62-3.60). CONCLUSIONS: Irrespective of whether they want to try quitting, when offered a tailored, self-help, text message stop smoking programme for pregnancy (MiQuit) as an adjunct to usual care, pregnant women are not more likely to stop smoking until childbirth but they report more attempts at stopping smoking.
dc.languageen
dc.publisherWiley
dc.subjectRESEARCH REPORT
dc.subjectRESEARCH REPORTS
dc.subjectpregnancy
dc.subjectself‐help
dc.subjectsmoking cessation
dc.subjecttext messaging
dc.titleEffectiveness of offering tailored text message, self-help smoking cessation support to pregnant women who want information on stopping smoking: MiQuit3 randomised controlled trial and meta-analysis.
dc.typeArticle
dc.date.updated2021-11-05T11:30:00Z
prism.publicationNameAddiction
dc.identifier.doi10.17863/CAM.77771
dcterms.dateAccepted2021-09-22
rioxxterms.versionofrecord10.1111/add.15715
rioxxterms.versionAO
rioxxterms.versionVoR
rioxxterms.licenseref.urihttp://creativecommons.org/licenses/by/4.0/
dc.contributor.orcidColeman, Tim [0000-0002-7303-4805]
dc.contributor.orcidClark, Miranda [0000-0002-6179-046X]
dc.contributor.orcidWelch, Charlie [0000-0002-2421-5538]
dc.contributor.orcidJones, Matthew [0000-0002-4824-9724]
dc.contributor.orcidNaughton, Felix [0000-0001-9790-2796]
dc.identifier.eissn1360-0443
pubs.funder-project-idCCF (None)
cam.issuedOnline2021-11-05


Files in this item

Thumbnail
Thumbnail

This item appears in the following Collection(s)

Show simple item record