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dc.contributor.authorBackman, Linda
dc.contributor.authorMöller, Marika C
dc.contributor.authorThelin, Eric P
dc.contributor.authorDahlgren, Daniel
dc.contributor.authorDeboussard, Catharina
dc.contributor.authorÖstlund, Gunilla
dc.contributor.authorLindau, Maria
dc.date.accessioned2021-11-16T00:30:34Z
dc.date.available2021-11-16T00:30:34Z
dc.date.issued2022-02-23
dc.identifier.issn0887-6177
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/330656
dc.description.abstractOBJECTIVE: To elaborate on possible cognitive sequelae related to COVID-19, associated cerebrovascular injuries as well as the general consequences from intensive care. COVID-19 is known to have several, serious CNS-related consequences, but neuropsychological studies of severe COVID-19 are still rare. METHODS: M., a 45-year-old man, who survived a severe COVID-19 disease course including Acute Respiratory Distress Syndrome (ARDS), cerebral microbleeds, and 35 days of mechanical ventilation, is described. We elaborate on M's recovery and rehabilitation process from onset to the 8-month follow-up. The cognitive functions were evaluated with a comprehensive screening battery at 4 weeks after extubation and at the 8-month follow-up. RESULTS: Following extubation, M. was delirious, reported visual hallucinations, and had severe sleeping difficulties. At about 3 months after COVID-19 onset, M. showed mild to moderate deficits on tests measuring processing speed, working memory, and attention. At assessments at 8 months, M. performed better, with results above average on tests measuring learning, memory, word fluency, and visuospatial functions. Minor deficits were still found regarding logical reasoning, attention, executive functioning, and processing speed. There were no lingering psychiatric symptoms. While M. had returned to a part-time job, he was not able to resume previous work-tasks. CONCLUSION: This case-study demonstrates possible cognitive deficits after severe COVID-19 and emphasizes the need of a neuropsychological follow-up, with tests sensitive to minor deficits. The main findings of this report provide some support that the long-term prognosis for cognition in severe COVID-19 may be hopeful.
dc.languageeng
dc.publisherOxford University Press (OUP)
dc.rightsAttribution-NonCommercial 4.0 International
dc.rights.urihttps://creativecommons.org/licenses/by-nc/4.0/
dc.subjectARDS
dc.subjectAssessment
dc.subjectCOVID-19
dc.subjectCase Report
dc.subjectExecutive functions
dc.subjectRehabilitation
dc.titleMonthlong Intubated Patient with Life-Threatening COVID-19 and Cerebral Microbleeds Suffers Only Mild Cognitive Sequelae at 8-Month Follow-up: A Case Report.
dc.typeArticle
prism.publicationNameArchives of Clinical Neuropsychology
dc.identifier.doi10.17863/CAM.78101
dcterms.dateAccepted2021-08-25
rioxxterms.versionofrecord10.1093/arclin/acab075
rioxxterms.versionVoR
rioxxterms.licenseref.urihttp://www.rioxx.net/licenses/all-rights-reserved
rioxxterms.licenseref.startdate2021-08-25
dc.contributor.orcidThelin, Eric [0000-0002-2338-4364]
dc.identifier.eissn1873-5843
rioxxterms.typeJournal Article/Review
cam.issuedOnline2021-09-17


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Attribution-NonCommercial 4.0 International
Except where otherwise noted, this item's licence is described as Attribution-NonCommercial 4.0 International