Understanding the effectiveness of government interventions against the resurgence of COVID-19 in Europe.
Authors
Rogers-Smith, Charlie
Snodin, Benedict
Ahuja, Janvi
Sandbrink, Jonas B
Altman, George
Dhaliwal, Gurpreet
Finnveden, Lukas
Norman, Alexander John
Sandkühler, Julia Fabienne
Aitchison, Laurence
Gavenčiak, Tomáš
Mellan, Thomas
Kulveit, Jan
Chindelevitch, Leonid
Publication Date
2021-10-05Journal Title
Nat Commun
ISSN
2041-1723
Publisher
Springer Science and Business Media LLC
Volume
12
Issue
1
Language
en
Type
Article
This Version
VoR
Metadata
Show full item recordCitation
Sharma, M., Mindermann, S., Rogers-Smith, C., Leech, G., Snodin, B., Ahuja, J., Sandbrink, J. B., et al. (2021). Understanding the effectiveness of government interventions against the resurgence of COVID-19 in Europe.. Nat Commun, 12 (1) https://doi.org/10.1038/s41467-021-26013-4
Description
Funder: European and Developing Countries Clinical Trials Partnership (EDCTP); doi: https://doi.org/10.13039/501100001713
Funder: MRC Centre for Global Infectious Disease Analysis (MR/R015600/1), jointly funded by the U.K. Medical Research Council (MRC) and the U.K. Foreign, Commonwealth and Development Office (FCDO), under the MRC/FCDO Concordat agreement. Community Jameel. The UK Research and Innovation (MR/V038109/1), the Academy of Medical Sciences Springboard Award (SBF004/1080), The MRC (MR/R015600/1), The BMGF (OPP1197730), Imperial College Healthcare NHS Trust- BRC Funding (RDA02), The Novo Nordisk Young Investigator Award (NNF20OC0059309) and The NIHR Health Protection Research Unit in Modelling Methodology. S. Bhatt thanks Microsoft AI for Health and Amazon AWS for computational credits.
Funder: EA Funds
Funder: University of Oxford (Oxford University); doi: https://doi.org/10.13039/501100000769
Funder: DeepMind
Funder: OpenPhilanthropy
Funder: UKRI Centre for Doctoral Training in Interactive Artificial Intelligence (EP/S022937/1)
Funder: Augustinus Fonden (Augustinus Foundation); doi: https://doi.org/10.13039/501100004954
Funder: Knud Højgaards Fond (Knud Højgaard Fund); doi: https://doi.org/10.13039/501100009938
Funder: Kai Lange og Gunhild Kai Langes Fond (Kai Lange and Gunhild Kai Lange Foundation); doi: https://doi.org/10.13039/501100008206
Funder: Aage og Johanne Louis-Hansens Fond (Aage and Johanne Louis-Hansen Foundation); doi: https://doi.org/10.13039/501100010344
Funder: William Demant Foundation
Funder: Boehringer Ingelheim Fonds (Stiftung für medizinische Grundlagenforschung); doi: https://doi.org/10.13039/501100001645
Funder: Imperial College COVID-19 Research Fund
Funder: Cancer Research UK (CRUK); doi: https://doi.org/10.13039/501100000289
Abstract
European governments use non-pharmaceutical interventions (NPIs) to control resurging waves of COVID-19. However, they only have outdated estimates for how effective individual NPIs were in the first wave. We estimate the effectiveness of 17 NPIs in Europe's second wave from subnational case and death data by introducing a flexible hierarchical Bayesian transmission model and collecting the largest dataset of NPI implementation dates across Europe. Business closures, educational institution closures, and gathering bans reduced transmission, but reduced it less than they did in the first wave. This difference is likely due to organisational safety measures and individual protective behaviours-such as distancing-which made various areas of public life safer and thereby reduced the effect of closing them. Specifically, we find smaller effects for closing educational institutions, suggesting that stringent safety measures made schools safer compared to the first wave. Second-wave estimates outperform previous estimates at predicting transmission in Europe's third wave.
Keywords
Basic Reproduction Number, COVID-19, Europe, Government, Humans, Models, Theoretical, SARS-CoV-2, Time Factors
Sponsorship
RCUK | Engineering and Physical Sciences Research Council (EPSRC) (EP/S024050/1, EP/V002910/1, EP/S024050/1))
RCUK | Biotechnology and Biological Sciences Research Council (BBSRC) (BB/T008784/1)
Identifiers
s41467-021-26013-4, 26013
External DOI: https://doi.org/10.1038/s41467-021-26013-4
This record's URL: https://www.repository.cam.ac.uk/handle/1810/331498
Rights
Licence:
http://creativecommons.org/licenses/by/4.0/
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