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dc.contributor.authorPiotrowski, Jędrzej
dc.contributor.authorTimler, Małgorzata
dc.contributor.authorKozłowski, Remigiusz
dc.contributor.authorStasiak, Arkadiusz
dc.contributor.authorStasiak, Joanna
dc.contributor.authorBissinger, Andrzej
dc.contributor.authorTimler, Dariusz
dc.contributor.authorTimler, Wojciech
dc.contributor.authorMarczak, Michał
dc.contributor.authorZałuska, Roman
dc.contributor.authorPiotrowski, Grzegorz
dc.date.accessioned2021-12-24T14:37:48Z
dc.date.available2021-12-24T14:37:48Z
dc.date.issued2021-12-06
dc.identifier.issn2039-7275
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/331807
dc.description.abstract(1) Our study aimed to look at the clinical characteristics, treatment and short-term outcomes of patients hospitalized due to heart failure with coexisting cancer. (2) Methods: Seventy one cancer (Ca) patients and a randomly selected 70 patients without Ca, hospitalized due to heart failure exacerbation in the same time period constituted the study group (Ca patient group) and controls (non-Ca group), respectively. Data on clinical characteristics were collected retrospectively for both groups. (3) Results: Cancer patients presented with a less advanced NYHA class, had more frequent HFpEF, a higher peak troponin T level, and smaller left atrium size, as compared with controls. The in-hospital deaths of Ca patients were associated with: a higher New York Heart Association (NYHA) class, lower HgB level, worse renal function, higher K and AST levels, presence of diabetes mellitus, and HFpEF. By multivariate logistic regression analysis, impaired renal function was the only independent predictor of in-hospital death in Ca patients (OR-1.15; CI 1.05; 1.27); p = 0.017). The following covariates entered the regression: NYHA class, HgB, GFR, K+, AST, diabetes mellitus t.2, and HFpEF. (4) Conclusions: The clinical picture and the course of heart failure in patients with and without cancer are different.
dc.languageen
dc.publisherMDPI AG
dc.subjectcancer
dc.subjectheart failure
dc.subjecttreatment
dc.subjectshort-term outcome
dc.titleClinical Characteristics, Treatment, and Short-Term Outcome in Patients with Heart Failure and Cancer.
dc.typeArticle
dc.date.updated2021-12-24T14:37:48Z
prism.endingPage941
prism.issueIdentifier4
prism.publicationNameClin Pract
prism.startingPage933
prism.volume11
dc.identifier.doi10.17863/CAM.79256
dcterms.dateAccepted2021-11-29
rioxxterms.versionofrecord10.3390/clinpract11040107
rioxxterms.versionVoR
rioxxterms.licenseref.urihttps://creativecommons.org/licenses/by/4.0/
dc.contributor.orcidKozłowski, Remigiusz [0000-0003-2781-5341]
dc.contributor.orcidStasiak, Arkadiusz [0000-0002-7953-4739]
dc.contributor.orcidTimler, Dariusz [0000-0002-5415-5660]
dc.contributor.orcidZałuska, Roman [0000-0001-6408-3843]
dc.identifier.eissn2039-7283
cam.issuedOnline2021-12-06


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