Multi-scale analysis of turbulence–flame interaction is performed using experimental data sets from three methane- and propane-fired premixed, turbulent V-flames, at an approach flow turbulent Reynolds number of 450 and a ratio of r.m.s. fluctuating velocity from the mean to laminar flame speed of between 2.1 and 3.0, straddling the border between corru- gated flamelets and thin reaction zone in the Borghi-Peters diagram. The measurements were made in the plane of a single laser sheet using stereo particle image velocimetry SPIV and planar laser-induced fluorescence to measure three orthogonal components of velocity and flame OH. Methods to approximate the remaining, unmeasured, out of plane deriva- tives are described. The instantaneous SPIV images were bandpass filtered at user-specified characteristic length scales Lω and Ls (for vorticity and strain rate, respectively) resulting ininstantaneousbandpass-filteredvelocityfields,uLω anduLs,whichwerefurtheranalysed bb to give the bandpass filtered vorticity field, ωLω = ∇ × uLω , the strain-rate field, eLs , and the tangential strain rate field aLs . T This work quantifies two aspects of turbulence-flame interaction. The first aspect is that of the flame interaction of eddies of size Ls on the turbulence, as found by the statistics of the alignment of vorticity with strain rate. We find that vortical eddies with scale about Lω = 2δth (where δth is the flame thickness) are stretched by Ls structures which are larger than about 2 Lω, with this factor broadly true also for vortical eddies of scales Lω = 4δth and Lω = 6δth. Within the limitations of the data set, these findings are consistent with those in the literature on reacting and non-reacting flows, suggesting that the premixed flame has had little influence on the vortex stretching mechanism. The second aspect of turbulence-flame interaction examined is that of flame surface- averaged tangential strain rate imparted by eddies. Eddies with length scales Ls smaller than 2δth have the strongest individual contribution but eddies of this length scale and smaller contribute only about 1/3 of the total tangential strain rate. This is larger than the 10 % that has been reported in the literature based on analysis of DNS predictions of premixed flames at turbulent Reynolds numbers up to 110. Eddies with length scale Ls larger than about 20δth contribute a negligible amount to the total tangential strain rate. We have found no evidence that the Lewis number up to about 1.8 has an observ- able effect, but this may reflect the inability of the current instruments to resolve vortical structures down to Lω = δth. In the context of large eddy simulations (LES) of premixed combustion, these results are preliminary experimental evidence into the suggestion that resolving turbulence scales down to a few multiples of δth might be adequate to capture much of the flame straining caused by turbulence.