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dc.contributor.authorTritos, Nicholas A
dc.contributor.authorFazeli, Pouneh K
dc.contributor.authorMcCormack, Ann
dc.contributor.authorMallea-Gil, Susana M
dc.contributor.authorPineyro, Maria M
dc.contributor.authorChrist-Crain, Mirjam
dc.contributor.authorFrara, Stefano
dc.contributor.authorLabadzhyan, Artak
dc.contributor.authorIoachimescu, Adriana G
dc.contributor.authorShimon, Ilan
dc.contributor.authorTakahashi, Yutaka
dc.contributor.authorGurnell, Mark
dc.contributor.authorFleseriu, Maria
dc.contributor.author“Pituitary Society Delphi Collaborative Group”
dc.date.accessioned2022-02-07T16:20:50Z
dc.date.available2022-02-07T16:20:50Z
dc.date.issued2022-02
dc.identifier.issn1386-341X
dc.identifier.others11102-021-01170-3
dc.identifier.other1170
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/333715
dc.description.abstractPURPOSE: In adults and children, transsphenoidal surgery (TSS) represents the cornerstone of management for most large or functioning sellar lesions with the exception of prolactinomas. Endocrine evaluation and management are an essential part of perioperative care. However, the details of endocrine assessment and care are not universally agreed upon. METHODS: To build consensus on the endocrine evaluation and management of adults undergoing TSS, a Delphi process was used. Thirty-five statements were developed by the Pituitary Society's Education Committee. Fifty-five pituitary endocrinologists, all members of the Pituitary Society, were invited to participate in two Delphi rounds and rate their extent of agreement with statements pertaining to perioperative endocrine evaluation and management, using a Likert-type scale. Anonymized data on the proportion of panelists' agreeing with each item were summarized. A list of items that achieved consensus, based on predefined criteria, was tabulated. RESULTS: Strong consensus (≥ 80% of panelists rating their agreement as 6-7 on a scale from 1 to 7) was achieved for 68.6% (24/35) items. If less strict agreement criteria were applied (ratings 5-7 on the Likert-type scale), consensus was achieved for 88% (31/35) items. CONCLUSIONS: We achieved consensus on a large majority of items pertaining to perioperative endocrine evaluation and management using a Delphi process. This provides an international real-world clinical perspective from an expert group and facilitates a framework for future guideline development. Some of the items for which consensus was not reached, including the assessment of immediate postoperative remission in acromegaly or Cushing's disease, represent areas where further research is needed.
dc.languageen
dc.publisherSpringer Science and Business Media LLC
dc.subjectArticle
dc.subjectDelphi process
dc.subjectPituitary adenoma
dc.subjectTranssphenoidal surgery
dc.subjectHypopituitarism
dc.subjectPerioperative
dc.subjectPostoperative assessment
dc.titlePituitary Society Delphi Survey: An international perspective on endocrine management of patients undergoing transsphenoidal surgery for pituitary adenomas.
dc.typeArticle
dc.date.updated2022-02-07T16:20:49Z
prism.endingPage73
prism.issueIdentifier1
prism.publicationNamePituitary
prism.startingPage64
prism.volume25
dc.identifier.doi10.17863/CAM.81132
dcterms.dateAccepted2021-07-01
rioxxterms.versionofrecord10.1007/s11102-021-01170-3
rioxxterms.versionVoR
rioxxterms.licenseref.urihttp://creativecommons.org/licenses/by/4.0/
dc.contributor.orcidTritos, Nicholas A [0000-0001-8867-607X]
dc.contributor.orcidFazeli, Pouneh K [0000-0003-1731-2927]
dc.contributor.orcidFrara, Stefano [0000-0002-1308-5598]
dc.contributor.orcidGurnell, Mark [0000-0001-5745-6832]
dc.contributor.orcidFleseriu, Maria [0000-0001-9284-6289]
dc.identifier.eissn1573-7403
cam.issuedOnline2021-07-20


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